Purified anti-Keratin 14 Antibody
- 产品名称：
- Purified anti-Keratin 14 Antibody
- 产品类别：
- 抗体
- 产品编号：
- 905303
- 产品应用：
- 905303
- Verified Reactivity
- Human, Mouse, Rat
- Reported Reactivity
- Dog, Non-Human Primate
- Antibody Type
- Polyclonal
- Host Species
- Rabbit
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
IHC-P - Quality tested
ICC, WB - Verified
- Recommended Usage
Each lot of this antibody is quality control tested by formalin-fixed paraffin-embedded immunohistochemical staining. For immunohistochemistry, a concentration range of 0.1 - 10 μg/ml is suggested. For Western blotting, a concentration range of 0.5 - 2 ug/ml (1:250-1:1000)?is suggested. For immunocytochemistry, a concentration range of 0.5?- 2.0?μg/ml (1:250 - 1:1000)?is recommended.?It is recommended that the reagent be titrated for optimal performance for each application.
- Application Notes
This product may contain other non-IgG subtypes.
- Application References
(PubMed link indicates BioLegend citation) -
- Hu Y, et al. 2001. Nature 410:710. PubMed
- Yuspa SH, et al. 1989. J. Cell. Biol. 109:1207. PubMed
- ?
- Product Citations
-
- Miyauchi K, et al. 2021. Front Immunol. 12:663177. PubMed
- Fu R, et al. 2019. Nat Commun. 10:3210. PubMed
- Changarathil G, et al. 2019. PLoS One. 14:e0215908. PubMed
- Abbasi S, et al. 2020. Cell Stem Cell. 27(3):396-412.e6. PubMed
- Moehring F et al. 2018. eLife. 7 pii: e31684. PubMed
- Yang K, et al. 2022. J Clin Invest. 132:. PubMed
- Yip HYK, et al. 2021. STAR Protocols. 2(3):100765. PubMed
- Altmeier S, et al. 2016. PLoS Pathog. 12: 1005882. PubMed
- Guo Q, et al. 2022. Nat Commun. 13:3837. PubMed
- Ishii R, et al. 2020. Development. . PubMed
- Jones KB et al. 2018. Cell stem cell. 24(1):183-192 . PubMed
- Wang R, et al. 2021. Front Cell Dev Biol. 9:772669. PubMed
- Adams CR, et al. 2019. Elife. 8. PubMed
- Yip HYK, et al. 2020. Molecular Cell. 80(2):279-295.e8. PubMed
- Reehorst CM, et al. 2021. Development. 148:. PubMed
- Johansson E, et al. 2021. Sci Rep. 11:22329. PubMed
- Nishiguchi MA et al. 2018. Cell reports. 24(13):3383-3392 . PubMed
- Christin JR, et al. 2020. Cell Reports. 31(10):107742. PubMed
- Koenig U, et al. 2019. Autophagy. :1. PubMed
- Pruett L, et al. 2021. J Mater Chem B. 9:7132. PubMed
- Cowie AM et al. 2018. The Journal of Neuroscience. 38(25):5807-5825 . PubMed
- Giraddi RR et al. 2018. Cell reports. 24(6):1653-1666 . PubMed
- Anderton H, et al. 2018. Cell Death Differ. 26:877. PubMed
- Zhong Z, et al. 2021. Biomaterials. 267:120462. PubMed
- Ishii R, et al. 2020. Development. . PubMed
- Anderton H, et al. 2017. J Invest Dermatol. 137:2371. PubMed
- RRID
- AB_2734678 (BioLegend Cat. No. 905303) AB_2616896 (BioLegend Cat. No. 905304)
- Structure
- Keratin 14 is a 472 amino acid protein with a molecular mass of 52 kD.
- Distribution
-
Tissue distribution: skin.
Cellular distribution: extracellular, nucleus, cytoskeleton, and cytosol.
- Function
- Nonhelical tail domain is involved in promoting KRT5-KRT14 filaments to self-organize into large bundles, enhances the mechanical properties involved in resilience of keratin intermediate filaments in vitro.
- Biology Area
- Cell Biology, Cell Motility/Cytoskeleton/Structure, Neuroscience, Neuroscience Cell Markers
- Molecular Family
- Intermediate Filaments
- Antigen References
-
1. Wend P, et al. 2013. EMBO J. 32(14):1977-89. PubMed
2. Welm AL, et al. 2005. Proc. Natl. Acad. Sci. USA 102(12):4324. (IHC) PubMed
3. Liang Y. 2011. Pathalog. Res. Int. 2011:93674. (IHC) PubMed
- Gene ID
- 3861 View all products for this Gene ID
- UniProt
- View information about Keratin 14 on UniProt.org
