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Purified anti-Loricrin Antibody
产品名称:
Purified anti-Loricrin Antibody
产品类别:
抗体
产品编号:
905103
产品应用:
905103
[价格]
规格 价格 库存
25µg ¥ 1750 1

产品详情

Product Details

Verified Reactivity
Human
Antibody Type
Polyclonal
Host Species
Rabbit
Immunogen
This antibody was raised against a peptide sequence derived from the C-terminus of the mouse loricrin protein.
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/mL
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.
Application

IHC-P - Quality tested
WB - Verified

Recommended Usage

Each lot of this antibody is quality control tested by formalin-fixed paraffin-embedded immunohistochemical staining. For immunohistochemisty, a concentration range of 1.0 - 10 μg/mL is suggested. For Western blotting, a usage of 1.0 μg/mL is suggested. It is recommended that the reagent be titrated for optimal performance for each application.

Application Notes

This product may contain other non-IgG subtypes.

Application References

(PubMed link indicates BioLegend citation)
  1. Suzuki K, et al. 2009. Development 136:367. (IHC-P) PubMed
Product Citations
  1. Moriyama M, et al. 2016. PLoS One. 11:e0164799. PubMed
  2. Wong W, et al. 2020. PLoS One. 15:e0241617. PubMed
  3. Muhsen M, et al. 2019. PLoS One. 14:e0210504. PubMed
  4. Tremblay A, et al. 2021. Int J Mol Sci. 22:. PubMed
  5. Shih YH, et al. 2020. J Invest Dermatol. 1100:140. PubMed
  6. Trompette A, et al. 2022. Mucosal Immunol. :. PubMed
  7. Loomis KH, et al. 2021. Microbiome. 9:22. PubMed
  8. Reehorst CM, et al. 2021. Development. 148:. PubMed
  9. Zhang Z, et al. 2018. Nat Med. 24:617. PubMed
  10. Moon H, et al. 2019. Nat Commun. 10:2225. PubMed
  11. Nishiguchi MA et al. 2018. Cell reports. 24(13):3383-3392 . PubMed
  12. Liu F, et al. 2021. Cell Reports. 35(10):109225. PubMed
RRID
AB_2734676 (BioLegend Cat. No. 905103) AB_2616895 (BioLegend Cat. No. 905104)

Antigen Details

Structure
Loricrin is a 312 amino acid protein with a molecular mass of 26 kD. Observed MW for human may also be 35 kD.
Distribution

Tissue distribution: skin.
Cellular distribution: nucleus and plasma membrane.

Biology Area
Cell Biology, Cell Motility/Cytoskeleton/Structure
Antigen References

1. Wallace L. 2012. J. Cell Sci. 125:1750. (IHC, WB) PubMed
2. Bayo P, et al. 2008. Endocrinology 149:1377. (IHC) PubMed
3. Hu Y, et al. 2001. Nature 410:710. PubMed
4. Croyle MJ, et al. 2011. Development 138:1675. (IF) PubMed
5. Sengupta A, et al. 2010. PLoS One 5(8):e12249. (IHC) PubMed
6. Liakath-Ali K, et al. 2014. Nat. Commun. 5:3540. (IF) PubMed

Gene ID
4014 View all products for this Gene ID
UniProt
View information about Loricrin on UniProt.org

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