Purified anti-Aph-1a, 245-265 (C terminus) Antibod
- 产品名称：
- Purified anti-Aph-1a, 245-265 (C terminus) Antibod
- 产品类别：
- 抗体
- 产品编号：
- 823101
- 产品应用：
- 823101
- Verified Reactivity
- Human
- Antibody Type
- Polyclonal
- Host Species
- Rabbit
- Immunogen
- The antibody Aph-1a, 245-265 (Poly18231) was raised against the human Aph-1aL/C-terminal region and recognizes the sequence CRRQEDSRVMVYSALRIPPED of human Aph-1aL.
- Formulation
- Phosphate-buffered solution, pH 7.2.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 1.0 mg/mL
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C. Please note the storage condition for this antibody has been changed from -20°C to between 2°C and 8°C. You can also check your vial or your CoA to find the most accurate storage condition for this antibody.
- Application
-
WB, ICC
- Recommended Usage
Each lot of this antibody is quality control tested by Western blotting.
The optimal working dilution should be determined for each specific assay condition.
? WB: 1:1,000*
- Application Notes
This antibody is effective in immunoblotting (WB).
*Expected MW: 29 kD
WB Positive Control: Human Brain lysate
BioLegend also offers Poly18232 (823201) which recognizes residues 92-115 of the Aph-1aL/ S Loop.
This product may contain other non-IgG subtypes.
- Application References
(PubMed link indicates BioLegend citation) -
- Gu Y, Chen F, Sanjo N, Kawarai T, Hasegawa H, Duthie M, Li W, Ruan X, Luthra A, Mount HT, Tandon A, Fraser PE, St George-Hyslop P. Aph-1 interacts with mature and immature forms of presenilins and nicastrin and may play a role in maturation of the presenilin.nicastrin complexes. J Biol Chem 278:7374-7380, 2003.
- Product Citations
-
- Lu J, et al. 2016. PLoS One. 11:e0166415. PubMed
- RRID
- AB_2564862 (BioLegend Cat. No. 823101)
