APC anti-human CD74 (Cytoplasmic) Antibody -上海雅吉生物科技有限公司

规格	价格	库存
25tests	￥ 1666	1

Product Details

Verified Reactivity: Human
Antibody Type: Monoclonal
Host Species: Mouse
Immunogen: Synthetic peptide DQKPVMDDQRDLISNNE, corresponding to amino acids 12-28 of the cytoplasmic tail of human CD74.
Formulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation: The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions.
Concentration: Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
Storage & Handling: The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application: ICFC -?Quality tested
Recommended Usage: Each lot of this antibody is quality control tested by intracellular immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.
Excitation Laser: Red Laser (633 nm)
RRID: AB_2716216 (BioLegend Cat. No. 357605) AB_2716217 (BioLegend Cat. No. 357606)

Structure: Type II transmembrane glycoprotein, 33, 35, 41, 43 kD
Distribution: B cells and other antigen presenting cells, activated T cells, activated endothelial and epithelial cells, and certain carcinomas
Function: Regulate loading of exogenous peptides onto MHC class II and B cell differentiation, involved in positive selection of CD4+ T cells.
Interaction: Associates with MHC II
Ligand/Receptor: HLA-DR, MIF, H. pylori urease B, associate with CD44
Cell Type: Antigen-presenting cells, B cells, Endothelial cells, Epithelial cells, T cells
Biology Area: Immunology, Innate Immunity
Molecular Family: CD Molecules, MHC Antigens
Antigen References: 1. Koch N, et al. 1991. J. Immunol. 147:2643.
2. Wilson KM, et al. 1993. Immunology 79:331.
3. Moldenhauer G, et al. 1999. Immunology 96:473.
4. Shi X, et al. 2006. Immunity 25:595.
5. Beswick EJ, et al. 2006. Infect. Immun. 74:1148.
6. Zola H, et al. 2007. Leukocyte and Stromal Cell Molecules: The CD Markers Wiley-Liss A John Wiley & Sons Inc, Publication.
Gene ID: 972 View all products for this Gene ID
UniProt: View information about CD74 on UniProt.org