Alexa Fluor® 594 anti-Nucleophosmin Antibody
- 产品名称：
- Alexa Fluor® 594 anti-Nucleophosmin Antibody
- 产品类别：
- 抗体
- 产品编号：
- 686803
- 产品应用：
- 686803
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Purified recombinant human nucleophosmin (2-265 a.a.) expressed in E. coli.
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography and conjugated with Alexa Fluor? 594 under optimal conditions.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
ICC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunocytochemistry. For immunocytochemistry, a concentration range of 0.2 - 1.0 μg/ml is recommended. It is recommended that the reagent be titrated for optimal performance for each application.
* Alexa Fluor? 594 has an excitation maximum of 590 nm, and a maximum emission of 617 nm.
Alexa Fluor? and Pacific Blue? are trademarks of Life Technologies Corporation.
View full statement regarding label licenses - RRID
- AB_2617022 (BioLegend Cat. No. 686803)
- Structure
- 294 amino acids with a predicted molecular weight of 33 kD.
- Distribution
-
Nucleolus.
- Function
- Involved in ribosome biogenesis, centrosome duplication, protein chaperoning, histone assembly, cell proliferation, and regulation of tumor suppressors p53/TP53 and ARF.
- Interaction
- NSUN2, SENP3, hepatitis delta virus S-HDAg, HTLV1 Rex protein, methylated form of RPS10, APEX1, NEK2, ROCK2 and BRCA2, RPGR, CENPW, EIF2AK2/PKR, CEBPA (isoform 4), and DDX31.
- Biology Area
- Cell Biology
- Molecular Family
- Phospho-Proteins
- Antigen References
-
1. Szebeni A, et al. 2003. J. Biol. Chem. 278:9107.
2. Colombo E, et al. 2002. Nat. Cell Biol. 4:529.
3. Chan PK, et al. 1986. J. Biol. Chem. 261:14335.
- Gene ID
- 4869 View all products for this Gene ID
- UniProt
- View information about Nucleophosmin on UniProt.org
