Purified anti-BCL10 Antibody -上海雅吉生物科技有限公司

规格	价格	库存
100µg	￥ 3710	1

Product Details

Verified Reactivity: Human, Mouse
Antibody Type: Monoclonal
Host Species: Mouse
Immunogen: Purified recombinant fragment of human BCL10 expressed in E. Coli.
Formulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation: The antibody was purified by affinity chromatography.
Concentration: 0.5 mg/ml
Storage & Handling: The antibody solution should be stored undiluted between 2°C and 8°C.
Application: WB - Quality tested
Recommended Usage: Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 0.5 - 2.0 ?g per ml. It is recommended that the reagent be titrated for optimal performance for each application.
Application Notes: Reacts with mouse BCL10.
RRID: AB_2572170 (BioLegend Cat. No. 684702)

Structure: 233 amino acids with the predicted molecular weight of approximately 26kD with the characteristic of caspase recruitment domain.
Distribution: BCL10 is expressed in all normal and malignant tissues. In the lymphoid tissue, it is highly expressed in the germinal center but low in the mantle zone, and intermediate in the marginal zone.
Function: Antigen-receptor-mediated lymphocyte activation through the NF-κB pathway.
Interaction: CARMA1, CARD9, 10 and 14, MALT1, BCR, TCR
Cell Type: B cells, Neutrophils
Biology Area: Apoptosis/Tumor Suppressors/Cell Death, Cancer Biomarkers, Cell Biology, Cell Cycle/DNA Replication, Cell Motility/Cytoskeleton/Structure, Immunology, Innate Immunity, Signal Transduction, Transcription Factors, Ubiquitin/Protein Degradation
Antigen References: 1. Turvey SE, et al. 2014. J. Allergy Clin. Immunol. 134:276.
2. Thome M, et al. 2010. Cold Spring Harb. Perspect. Biol. 2:a003004.
3. Thome M, et al. 2007. Trends Immunol. 28:281.
4. Pérez de Diego R, et al. 2015. J. Allergy Clin. Immunol. 136:1139.
5. Sun W, et al. 2010. Cell Signal. 22:1799.
6. Jost P, et al. 2006. Curr. Drug Targets 7:1335.
7. Lin X, et al. 2004. Semin. Immunol. 16:429.
8. Thome M, et al. 2004. Nat. Rev. Immunol. 4:348.
9. Marion S, et al. 2012. Dev. Cell 5:954-967.
Gene ID: 8915 View all products for this Gene ID
UniProt: View information about BCL10 on UniProt.org