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Purified anti-SKP1 Antibody
产品名称:
Purified anti-SKP1 Antibody
产品类别:
抗体
产品编号:
605651
产品应用:
605651
[价格]
规格 价格 库存
25µg ¥ 1652 1

产品详情

Product Details

Verified Reactivity
Human, Mouse
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
Recombinant full length human SKP1
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/mL
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.
Application

WB - Quality tested
ICC - Verified

Recommended Usage

Each lot of this antibody is quality control tested by western blotting. For western blotting, the suggested use of this reagent is 0.25 - 1.0 ?g/mL. For immunocytochemistry, a concentration range of 2.5 - 5.0 μg/mL is recommended. It is recommended that the reagent be titrated for optimal performance for each application.

Application Notes

For ICC, we recommend fixation with MeOH. Fixation in 4% PFA followed by permeabilization with MeOH, and fixation in 4% PFA followed by permeabilization with 0.5% Triton X-100 were both tested but produced weak staining.

This clone is not recommended for IHC-P. Testing was conducted using formalin-fixed paraffin-embedded human testis but only a faint signal was produced

RRID
AB_2924614 (BioLegend Cat. No. 605651) AB_2924614 (BioLegend Cat. No. 605652)

Antigen Details

Structure
SKP1 is a 163 amino acid protein with a predicted molecular weight of 19 kD.
Distribution

Localized to the centrosome, cytosol, nucleus, and nucleoplasm/ubiquitously expressed

Function
Host-virus interaction, Ubl conjugation pathway, Ubiquitin/Protein Degradation, Adaptor Protein
Biology Area
Cell Biology, Cell Cycle/DNA Replication, DNA Repair/Replication, Ubiquitin/Protein Degradation
Molecular Family
GTPases
Antigen References
  1. Piva R, et al. 2002. Mol?Cell?Biol. 22:8375-87.
  2. Thompson L, et al. 2022. Front?Cell Dev Biol. 10:3389.
  3. Yongjuan G, et al. 2020. Sci?Adv. 6:22129.
Gene ID
6500 View all products for this Gene ID
UniProt
View information about SKP1 on UniProt.org

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