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Purified anti-HSP60 Antibody
产品名称:
Purified anti-HSP60 Antibody
产品类别:
抗体
产品编号:
681502
产品应用:
681502
[价格]
规格 价格 库存
100µg ¥ 4032 1

产品详情

Product Details

Verified Reactivity
Human, Mouse, Rat
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
Purified recombinant fragment (265-462 a.a.) of human HSP60 expressed in E. coli.
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.
Application

WB - Quality tested
ICC - Verified

Recommended Usage

Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 0.5 - 2.5 ?g per ml.?For immunocytochemistry, a concentration range of 1.0 - 10 μg/ml is recommended. It is recommended that the reagent be titrated for optimal performance for each application.

Product Citations
  1. Di Gioia M, et al. 2020. Nat Immunol. 21:42. PubMed
RRID
AB_2566474 (BioLegend Cat. No. 681502)

Antigen Details

Structure
HSP60 contains 573 amino acids with a predicted molecular weight of 61 kD.
Distribution

Mitochondrial matrix.

Function
HSP60 plays important roles in trafficking, folding, and the assembly of mitochondrial proteins. Under stress conditions, it may prevent protein misfolding and aggregation.
Interaction
Interacts with HRAS (by similarity), HBV protein X, HTLV-1 protein p40tax, ATAD3A, METTL20, and METTL21B.
Ligand/Receptor
TLR4.
Biology Area
Cell Biology, Immunology, Innate Immunity, Mitochondrial Function, Neuroinflammation, Neuroscience, Neuroscience Cell Markers
Molecular Family
Mitochondrial Markers
Antigen References

1. Bukau B, Horwich AL. 1998. Cell 92:351.
2. Hansen JJ, et al. 2002. Am. J. Hum. Genet. 70:1328.
3. Kol A, et al. 2000. J. Immunol. 164:13.
4. Jindal S, et al. 1989. Mol. Cell Biol. 9:2279.
5. Magen D, et al. 2008. Am. J. Hum. Genet. 83:30.
6. Chandra D, et al. 2007. J. Biol. Chem. 282:31289.

Gene ID
3329 View all products for this Gene ID
UniProt
View information about HSP60 on UniProt.org

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