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Direct-Blot™ HRP anti-HSP60 Antibody
产品名称:
Direct-Blot™ HRP anti-HSP60 Antibody
产品类别:
抗体
产品编号:
681503
产品应用:
681503
[价格]
规格 价格 库存
100µL ¥ 4760 1

产品详情

Product Details

Verified Reactivity
Human, Mouse, Rat
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
Purified recombinant fragment (265-462 a.a.) of human HSP60 expressed in E. coli.
Formulation
This antibody is provided in 50% glycerol in aqueous buffered solutions with preservatives.
Preparation
The antibody was purified by affinity chromatography and conjugated with HRP under optimal conditions.
Concentration
Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
Storage & Handling
Upon receipt, the antibody solution should be stored undiluted at -20°C, and protected from prolonged exposure to light.
Application

WB - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested dilution is 1:1000-1:2000. The optimal dilution should be determined by titration for each individual assay of interest.

25 ?l and 100 ?l of Direct-Blot? HRP antibody can be used for approximately 5 and 20 Western blots, respectively, at the recommended concentration/dilution.

RRID
AB_2572011 (BioLegend Cat. No. 681503)

Antigen Details

Structure
HSP60 contains 573 amino acids with a predicted molecular weight of 61 kD.
Distribution

Mitochondrial matrix.

Function
HSP60 plays important roles in trafficking, folding, and the assembly of mitochondrial proteins. Under stress conditions, it may prevent protein misfolding and aggregation.
Interaction
Interacts with HRAS (by similarity), HBV protein X, HTLV-1 protein p40tax, ATAD3A, METTL20, and METTL21B.
Ligand/Receptor
TLR4.
Biology Area
Cell Biology, Immunology, Innate Immunity, Mitochondrial Function, Neuroinflammation, Neuroscience, Neuroscience Cell Markers
Molecular Family
Mitochondrial Markers
Antigen References

1. Bukau B, Horwich AL. 1998. Cell 92:351.
2. Hansen JJ, et al. 2002. Am. J. Hum. Genet. 70:1328.
3. Kol A, et al. 2000. J. Immunol. 164:13.
4. Jindal S, et al. 1989. Mol. Cell Biol. 9:2279.
5. Magen D, et al. 2008. Am. J. Hum. Genet. 83:30.
6. Chandra D, et al. 2007. J. Biol. Chem. 282:31289.

Gene ID
3329 View all products for this Gene ID
UniProt
View information about HSP60 on UniProt.org

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