Purified anti-PAK2 Antibody
- 产品名称：
- Purified anti-PAK2 Antibody
- 产品类别：
- 抗体
- 产品编号：
- 853401
- 产品应用：
- 853401
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Recombinant fragment of human PAK2 (a.a. 4-223) protein.
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/mL
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
WB - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 0.5 - 2.0 ?g/mL. It is recommended that the reagent be titrated for optimal performance for each application.
- Application Notes
This antibody specifically recognizes human PAK2 and does not cross-react with mouse or rat PAK2.
- RRID
- AB_2734648 (BioLegend Cat. No. 853401) AB_2734649 (BioLegend Cat. No. 853402)
- Structure
- PAK2 is a 524 amino acid protein with a molecular mass of 58 kD.
- Distribution
-
Tissue distribution: PAK2 is ubiquitously expressed. Higher expression levels of PAK2 are observed in skeletal muscle, ovary, thymus and spleen.
Cellular distribution: Nucleus.
- Function
- PAK2 is a serine/threonine protein kinase that plays a role in a variety of different signaling pathways including cytoskeleton regulation, cell motility, cell cycle progression, apoptosis, and proliferation.
- Interaction
- PAK2 interacts with CDC42/p21, RAC1, and SH3MD4.
- Cell Type
- Embryonic Stem Cells, Mesenchymal Stem Cells
- Biology Area
- Cell Biology, Neurodegeneration, Neuroscience, Protein Trafficking and Clearance, Stem Cells
- Molecular Family
- Enzymes and Regulators, Protein Kinases/Phosphatase
- Antigen References
-
- Fuchsova B, et al. 2016. Neuroscience. 333:331
- O’Hagan KL, et al. 2017. Sci Rep. 7:17097
- Koo KH and Kwon H. 2018. Cell Death Dis. 9:77
- Gene ID
- 5062 View all products for this Gene ID
- UniProt
- View information about PAK2 on UniProt.org
