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HRP anti-PAK2 Antibody
产品名称:
HRP anti-PAK2 Antibody
产品类别:
抗体
产品编号:
853403
产品应用:
853403
[价格]
规格 价格 库存
25µg ¥ 2058 1

产品详情

Product Details

Verified Reactivity
Human
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
Recombinant fragment of human PAK2 (a.a. 4-223) protein.
Formulation
This antibody is provided in 50% glycerol in aqueous buffered solutions with preservatives.
Preparation
The antibody was purified by affinity chromatography and conjugated with HRP under optimal conditions.
Concentration
0.5 mg/ml
Storage & Handling
Upon receipt, the antibody solution should be stored undiluted at -20°C, and protected from prolonged exposure to light.
Application

WB - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 0.1 - 0.5 ?g per ml. It is recommended that the reagent be titrated for optimal performance for each application.

Application Notes

This antibody specifically recognizes human PAK2 and does not cross-react with mouse or rat PAK2.

RRID
AB_2750552 (BioLegend Cat. No. 853403) AB_2750553 (BioLegend Cat. No. 853404)

Antigen Details

Structure
PAK2 is a 524 amino acid protein with a molecular mass of 58 kD.
Distribution

Tissue distribution: PAK2 is ubiquitously expressed. Higher expression levels of PAK2 are observed in skeletal muscle, ovary, thymus and spleen.
Cellular distribution: Nucleus.

Function
PAK2 is a serine/threonine protein kinase that plays a role in a variety of different signaling pathways including cytoskeleton regulation, cell motility, cell cycle progression, apoptosis, and proliferation.
Interaction
PAK2 interacts with CDC42/p21, RAC1, and SH3MD4.
Cell Type
Embryonic Stem Cells, Mesenchymal Stem Cells
Biology Area
Cell Biology, Neurodegeneration, Neuroscience, Protein Trafficking and Clearance, Stem Cells
Molecular Family
Enzymes and Regulators, Protein Kinases/Phosphatase
Antigen References
  1. Fuchsova B, et al. 2016. Neuroscience. 333:331
  2. O’Hagan KL, et al. 2017. Sci Rep. 7:17097
  3. Koo KH and Kwon H. 2018. Cell Death Dis. 9:77
Gene ID
5062 View all products for this Gene ID
UniProt
View information about PAK2 on UniProt.org

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