Purified anti-eIF-2A Antibody -上海雅吉生物科技有限公司

规格	价格	库存
100µg	￥ 3542	1

规格

价格

库存

100µg

￥ 3542

Product Details

Verified Reactivity: Human, Mouse
Antibody Type: Monoclonal
Host Species: Mouse
Immunogen: Purified recombinant fragment of human eIF-2A (448-576 a.a.) expressed in E. coli.
Formulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation: The antibody was purified by affinity chromatography.
Concentration: 0.5 mg/ml
Storage & Handling: The antibody solution should be stored undiluted between 2°C and 8°C.
Application: WB - Quality tested
Recommended Usage: Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 0.5 - 2.0 ?g per ml. It is recommended that the reagent be titrated for optimal performance for each application.
Application Notes: This antibody recognizes the protein translated from the gene EIF2A not to be confused with the protein translated from the gene EIF2S1, often referred to as eIF2-alpha in literature, and with which it shares the common name EIF2A.
RRID: AB_2629818 (BioLegend Cat. No. 690302)

Structure: 585 amino acids with a predicted molecular weight of 65kD. Contains two to four WD-repeats at the N-terminus and a coiled-coil at the C-terminus.
Distribution: Cytoplasm and nucleus.
Function: Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl-tRNAi to 40S ribosomal subunits.
Interaction: EIF2AK2, EIF3A, RIOK2, STAT1.
Biology Area: Cell Biology, Protein Synthesis
Antigen References: 1. Zoll WL, et al. 2002. J. Biol. Chem. 277:37079.
2. Kashiwagi K, et al. 2014. J. Struct. Funct. Genomics. 15:125.
3. Adams SL, et al. 1975. J. Biol. Chem. 250:9083.
4. Starck SR, et al. 2012. Science. 336:1719.
5. Starck SR, et al. 2008. PLoS One. 3:e3460.
6. Ingolia NT, et al. 2009. Science. 324:218.
7. Ingolia NT, et al. 2011. Cell. 147:789.
8. Kim JH, et al. 2011. EMBO J. 30:2454.
9. Ventoso I, et al. 2006. Genes Dev. 20:87.
Gene ID: 83939 View all products for this Gene ID
UniProt: View information about eIF-2alpha on UniProt.org