Purified anti-VAV Antibody
- 产品名称:
- Purified anti-VAV Antibody
- 产品类别:
- 抗体
- 产品编号:
- 935101
- 产品应用:
- 935101
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Partial recombinant human VAV1 (amino acid 121-324)
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/mL
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
WB - Quality tested
ICC, IP - Verified
Direct ELISA, FC - Reported in the literature, not verified in house
- Recommended Usage
Each lot of this antibody is quality control tested by western blotting. For western blotting, the suggested use of this reagent is 0.1 - 1.0 ?g/mL. For immunocytochemistry, a concentration range of 1.0 - 5.0 μg/mL is recommended. For immunoprecipitation, the suggested use of this reagent is 2 ?g/test. It is recommended that the reagent be titrated for optimal performance for each application.
- Application Notes
This clone does not recognize mouse VAV1.
Both methanol and Triton X-100 permeabilization produced correct staining in ICC testing.
- RRID
- AB_2832888 (BioLegend Cat. No. 935101) AB_2832889 (BioLegend Cat. No. 935102)
- Structure
- VAV1 is a 845 amino acid protein with a predicted molecular weight of 98 kD.
- Distribution
-
Cytosol/Hematopoeitic cells
- Function
- GEF, TCR signal transduction
- Biology Area
- Cell Biology
- Antigen References
-
- Costello P. et al. 1999. Proc Natl Acad Sci USA. 96:3035.
- Wülfing C. et al. 2000. Proc Natl Acad Sci USA. 97:10150.
- Villalba M, et al. 2001. J. Cell. Biol. 155:331.
- Tybulewicz V, et al. 2003. Immunological Reviews. 192:42.
- Katzav S. et al. 2004. Blood. 103:2443.
- Fernandez-Zapico M. et al. 2005. Cancer. Cell. 7:39.
- Gene ID
- 7409 View all products for this Gene ID
- UniProt
- View information about VAV on UniProt.org