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Purified anti-TCF8 (ZEB1) Antibody
产品名称:
Purified anti-TCF8 (ZEB1) Antibody
产品类别:
抗体
产品编号:
685602
产品应用:
685602
[价格]
规格 价格 库存
100µg ¥ 3710 1

产品详情

Product Details

Verified Reactivity
Human
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
Purified recombinant fragment of human ZEB1 (aa 967-1108) expressed in E. Coli.
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.
Application

WB - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 0.25 - 2.0 ?g per ml. It is recommended that the reagent be titrated for optimal performance for each application.

RRID
AB_2572205 (BioLegend Cat. No. 685602)

Antigen Details

Structure
Major isoform has 1,124 amino acids and a predicted molecular weight of 120 kD.
Distribution

Nucleus.

Function
Transcriptional repressor of IL-2, E-cadherin, BCL6, and RCOR1. Enhances or represses the promoter activity of the ATP1A1 gene, positively regulates neuronal differentiation, and promotes tumorigenicity by repressing stemness-inhibiting microRNAs.
Interaction
SMARCA4/BRG1.
Biology Area
Cell Biology, Signal Transduction, Transcription Factors
Antigen References

1. Postigo AA, et al. 2003. EMBO J. 22:2453.
2. Peinado H, et al. 2007. Nat. Rev. Cancer 7:415.
3. Karihtala P, et al. 2013. Breast Cancer Res. Treat. 138:81.
4. Bronsert P, et al. 2014. Surgery 156:97.
5. Liu Y, et al. 2014. Nat. Commun. 5:5660.
6. Zhang P, et al. 2015. Cell Cycle. 14:481.
7. Lehmann W, et al. 2016. Nat. Commun. 7:10498.

Gene ID
6935 View all products for this Gene ID
UniProt
View information about TCF8 on UniProt.org

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