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Biotin anti-Ubiquitin Antibody
产品名称:
Biotin anti-Ubiquitin Antibody
产品类别:
抗体
产品编号:
838707
产品应用:
838707
[价格]
规格 价格 库存
25µg ¥ 1904 1

产品详情

Product Details

Verified Reactivity
Human, Mouse, Rat, Drosophila
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
Clone P4G7 was raised against denatured bovine ubiquitin and recognizes ubiquitin, polyubiquitin, and ubiquitin-conjugated proteins.
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C. Do not freeze.
Application

IHC-P - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by formalin-fixed paraffin-embedded immunohistochemical staining. For immunohistochemistry, a concentration range of 0.5 - 5 ?g/ml is suggested. It is recommended that the reagent be titrated for optimal performance for each application.

Application Notes

P4G7 is equivalent to MAb P4D1. The ubiquitin protein is extremely well conserved and thus the antibody has extensive species cross-reactivity from yeast to human. This antibody was specifically developed to detect ubiquitin and ubiquitin-substrate conjugates by immunoblotting.

Application References

(PubMed link indicates BioLegend citation)
  1. Duttler S, et al. 2013. Mol. Cell. 3:379. (WB) PubMed
  2. Wu Y, et al. 2007. Mol. Cell. Biol. 18:6407. (WB) PubMed
RRID
AB_2801181 (BioLegend Cat. No. 838707) AB_2801182 (BioLegend Cat. No. 838708)

Antigen Details

Structure
Ubiquitin is a 76 amino acid protein with a molecular mass of 8.5 kD.
Distribution

Found in almost all tissues of eukaryotic organisms

Function
Regulatory protein
Biology Area
Cell Biology, Neurodegeneration, Neuroscience, Neuroscience Cell Markers, Protein Trafficking and Clearance, Signal Transduction
Molecular Family
Autophagosome Markers
Antigen References

1. Hatanaka H, et al. 2009. J. Biol. Chem. 23:15448. (WB) PubMed
2. Sarkari F, et al. 2013. J. Biol. Chem. 23:16975. (WB) PubMed

Gene ID
7316 View all products for this Gene ID
UniProt
View information about Ubiquitin on UniProt.org

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