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PE anti-human CD59 Antibody
产品名称:
PE anti-human CD59 Antibody
产品类别:
抗体
产品编号:
304707
产品应用:
304707
[价格]
规格 价格 库存
25tests ¥ 1442 1

产品详情

Product Details

Verified Reactivity
Human, Cynomolgus, Rhesus
Reported Reactivity
Baboon, Chimpanzee
Antibody Type
Monoclonal
Host Species
Mouse
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation
The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions.
Concentration
Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.

Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
Application References

(PubMed link indicates BioLegend citation)
  1. Schlossman S, et al. Eds. 1995. Leucocyte Typing V. Oxford University Press. New York.
Product Citations
  1. Fischer K, et al. 2016. Sci Rep. 6:29081. PubMed
  2. Xin Y, et al. 2021. Stem Cell Res Ther. 49:12. PubMed
  3. Davies L, et al. 2016. Stem Cells Trans Med. 5: 1485 - 1495. PubMed
  4. Tritschler H, et al. 2021. Cells. 10:. PubMed
  5. Lara S, et al. 2021. Eur J Immunol. . PubMed
  6. Plum T, et al. 2020. Immunity. 52(2):404-416. PubMed
  7. Cordero H, et al. 2021. Nat Commun. 12:5761. PubMed
RRID
AB_2275871 (BioLegend Cat. No. 304707) AB_2076125 (BioLegend Cat. No. 304708)

Antigen Details

Structure
Ly6 superfamily, single chain GPI-linked membrane protein, 19-25 kD
Distribution

All cell types

Function
Blocks complement-mediated lysis by inhibiting MAC formation
Ligand/Receptor
Complement components C8, C9
Biology Area
Cell Biology, Costimulatory Molecules, Immunology, Neuroinflammation, Neuroscience
Molecular Family
CD Molecules
Antigen References

1. Davies A, et al. 1993. Immunol. Res. 12:258.
2. Lachmann P. 1991. Immunol. Today 12:312.
3. Liszewski M, et al. 1996. Adv. Immunol. 61:201.

Gene ID
966 View all products for this Gene ID
UniProt
View information about CD59 on UniProt.org

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