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首页 > 抗体蛋白 > 抗体
Purified anti-Arginase 1 Antibody
产品名称：
Purified anti-Arginase 1 Antibody
产品类别：
抗体
产品编号：
678801
产品应用：
678801
[价格]
规格 价格 库存
25µg ￥ 1414 1

产品详情

Product Details

Verified Reactivity
Human, Mouse
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
Full length recombinant human ARG1 protein produced in HEK293T cells.
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.
Application

WB - Quality tested
KO/KD-WB, IHC-P - Verified
Recommended Usage

Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 0.5 - 2.0 ?g per mL.?For immunohistochemistry, a concentration range of 1 - 10 ?g/mL is suggested. It is recommended that the reagent be titrated for optimal performance for each application.

Product Citations
  1. Fitterer R, et al. 2020. J Clin Med. 9:00. PubMed
  2. Joseph R, et al. 2021. Br J Cancer. 125:176. PubMed
  3. Paredes F, et al. 2020. Circ Res. 126:41:00. PubMed
  4. Zhang X, et al. 2020. Arterioscler Thromb Vasc Biol. 40:597. PubMed
RRID
AB_2566050 (BioLegend Cat. No. 678801) AB_2566051 (BioLegend Cat. No. 678802)

Antigen Details

Structure
322 amino acids with a predicted molecular weight of approximately 35 kD.
Distribution

Expressed predominantly in the liver. It can also be induced in macrophages. Cytoplasmic.

Function
Arginase 1 plays an important role in processes such as wound healing, antiviral immune response, and atherosclerosis.
Interaction
Binds 2 manganese ions per subunit as a cofactor.
Ligand/Receptor
l-arginine.
Cell Type
Dendritic cells, Macrophages
Biology Area
Cell Biology, Neuroinflammation, Neuroscience
Molecular Family
Enzymes and Regulators
Antigen References

1. Wu G, et al. 1998. Biochem. J. 336:1.
2. El Kasmi KC, et al. 2008. Nat. Immunol. 9:1399.
3. Pesce JT, et al. 2009. PLoS Pathog. 5:e1000371.
4. Burrack KS, et al. 2014. Front Immunol. 5:428.
5. Pourcet B, et al. 2013. Trends Cardiovasc. Med. 23:143.
6. Bronte V, et al. 2003. Trends Immunol. 24:302.

Gene ID
383 View all products for this Gene ID
UniProt
View information about Arginase 1 on UniProt.org

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