首页 > 抗体蛋白 > 抗体
Purified anti-STING (TMEM173) Antibody
产品名称:
Purified anti-STING (TMEM173) Antibody
产品类别:
抗体
产品编号:
675902
产品应用:
675902
[价格]
规格 价格 库存
100µg ¥ 3710 1

产品详情

Product Details

Verified Reactivity
Human
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
Full length recombinant STING (TMEM173) protein produced in 293T cells.
Formulation
This antibody is provided in phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
Affinity purified.
Concentration
0.5 mg/ml
Storage & Handling
Upon receipt, store undiluted between 2°C and 8°C.
Application

WB - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is?1.0 - 2.0 ?g/ml (1:250-1:500).?It is recommended that the reagent be titrated for optimal performance for each application.

Product Citations
  1. Serrano R, et al. 2022. Oncoimmunology. 11:2030021. PubMed
  2. Kabelitz D, et al. 2022. Sci Rep. 12:17827. PubMed
RRID
AB_2565608 (BioLegend Cat. No. 675902)

Antigen Details

Structure
A 379 amino acid protein with a predicated molecular weight around 42 kD, and observed molecular weight on SDS gel is around 35 kD.
Distribution

STING is expressed in various hematopoietic cells such as T lymphocytes, NK cells, myeloid cells and monocytes and is also highly expressed in lung, ovary, heart, smooth muscle, retina, bone marrow and vagina.

Function
Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.
Interaction
MHC-II complex, DDX58/RIG-I, MAVS, SSR2, RNF5, TRIM56, TBK1, IFIT1 and IFIT2.
Cell Type
B cells, Monocytes, NK cells, T cells
Biology Area
Cell Biology, Immunology, Innate Immunity, Signal Transduction, Transcription Factors
Antigen References

1. Lemos H, et al. 2015. Expert Rev Clin Immunol. 11:155.
2. Konno H, et al. 2014. Microbes Infect. 16:998.
3. Maringer K, et al. 2014. Cytokine Growth Factor Rev. 25:669.
4. Cai X, et al. 2014. Mol Cell. 54:289.
5. Barber GN, et al. 2014. Trends Immunol. 35:88.
6. Sun L, et al. 2013. Science. 339:786.

Gene ID
340061 View all products for this Gene ID
UniProt
View information about STING on UniProt.org

联系我们

TEL:021-34661275  点击拨打热线