HRP anti-Beclin-1 Antibody
- 产品名称：
- HRP anti-Beclin-1 Antibody
- 产品类别：
- 抗体
- 产品编号：
- 849703
- 产品应用：
- 849703
- Verified Reactivity
- Human, Rat, Mouse
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Full length recombinant human Beclin-1 protein (NP_003757) produced in HEK293T cells
- Formulation
- This antibody is provided in 50% glycerol in aqueous buffered solutions with preservatives.
- Preparation
- The antibody was purified by affinity chromatography and conjugated with HRP under optimal conditions.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- Upon receipt, the antibody solution should be stored undiluted at -20°C, and protected from prolonged exposure to light.
- Application
-
WB - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 0.5 - 5.0 ?g per ml. It is recommended that the reagent be titrated for optimal performance for each application.
- Application References
(PubMed link indicates BioLegend citation) -
- Deng X, et al. 2017. Biochim. Biophys. Acta. 1862(3):337-350 (WB).
- RRID
- AB_2728575 (BioLegend Cat. No. 849703) AB_2728576 (BioLegend Cat. No. 849704)
- Structure
- Beclin-1 is a 450 amino acid protein with a molecular mass of 52 kD.
- Distribution
-
Tissue distribution: Beclin-1 is ubiquitously expressed.
Cellular distribution: Cytosol, endoplasmic reticulum, endosome, mitochondria, and nucleus.
- Function
- Beclin-1 is involved in autophagosome formation in autophagy.
- Biology Area
- Cell Biology, Neurodegeneration, Neuroscience, Neuroscience Cell Markers, Protein Trafficking and Clearance
- Molecular Family
- Autophagosome Markers
- Antigen References
-
- Cao Y, et al. 2007. Cell. Research 17:839?
- Gene ID
- 8678 View all products for this Gene ID
- UniProt
- View information about Beclin-1 on UniProt.org
