Purified anti-IGF2BP2 Antibody -上海雅吉生物科技有限公司

规格	价格	库存
100µg	￥ 4690	1

规格

价格

库存

100µg

￥ 4690

Product Details

Verified Reactivity: Human
Antibody Type: Monoclonal
Host Species: Mouse
Immunogen: Full length recombinant human IGF2BP2 protein (NP_006539) produced in HEK 293T cells.
Formulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation: The antibody was purified by affinity chromatography.
Concentration: 0.5 mg/ml
Storage & Handling: The antibody solution should be stored undiluted between 2°C and 8°C.
Application: WB - Quality tested
ICC - Verified
Recommended Usage: Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 0.5 - 2.5 ?g per ml. For immunocytochemistry, a concentration range of 0.1-10 μg/ml is recommended. It is recommended that the reagent be titrated for optimal performance for each application.
RRID: AB_2566241 (BioLegend Cat. No. 679602)

Structure: Canonical sequence contains 599 amino acids with a predicted molecular weight of 66.1 kD. Five isoforms with a molecular weight ranging from 54.7 kD to 61.8 kD.
Distribution: Nucleus, cytoplasm, and the cytoskeleton. It is expressed in oocytes, granulosa cells, Leydig cells, spermatogonia, but is expressed weaker in the lymph nodes, lungs, liver, kidney, heart muscles, spleen, and testis.
Function: IGF2BP2 binds to the 5' UTR of the insulin-like growth factor 2 (IGF2) mRNA and regulates IGF2 translation. It also modulates the cytoplasmic trafficking, turnover, and translation of various target mRNAs.
Interaction: Interacts with HNRPD, IGF2BP1, IGF2BP3, ELAVL1, DHX9, and HNRNPU.
Biology Area: Cell Biology, Transcription Factors
Antigen References: 1. Wachter K, et al. 2013. Biol. Chem. 394:1077.
2. Zhao Y, et al. 2012. DNA Cell Biol. 31:713.
3. Bell JL, et al. 2013. Cell Mol. Life Sci. 15:2657.
4. Ng MC, et al. 2008. Diabetes 57:2226.
5. Scott LJ, et al. 2007. Science 316:1341.
6. Nielsen FC, et al. 2002. J. Cell Sci. 115:2087.
7. Nielsen J, et al. 1999. Mol. Cell Biol. 2:1262.
Gene ID: 10644 View all products for this Gene ID
UniProt: View information about IGF2BP2 on UniProt.org