Purified anti-Gephyrin Antibody
- 产品名称：
- Purified anti-Gephyrin Antibody
- 产品类别：
- 抗体
- 产品编号：
- 856101
- 产品应用：
- 856101
- Verified Reactivity
- Human, Mouse, Rat
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Human recombinant gephyrin expressed in human HEK293T cells.
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
WB - Quality tested
IHC-P - Verified
- Recommended Usage
Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 0.5 - 5.0 ?g per ml. For immunohistochemistry, a concentration range of 5.0 - 10 ?g/ml is suggested. It is recommended that the reagent be titrated for optimal performance for each application.
- RRID
- AB_2783450 (BioLegend Cat. No. 856101) AB_2783451 (BioLegend Cat. No. 856102)
- Structure
- Gephyrin is a 736 amino acid protein with an apparent molecular mass of ~ 93 kD.
- Distribution
-
Tissue Distribution: Nervous system, endocrine system, and gastrointestinal tract.
Cellular Distribution: Plasma membrane, cytoskeleton, and cytosol.
- Function
- Gephyrin is a scaffolding protein that anchors inhibitory neurotransmitter receptors to the postsynaptic cytoskeleton.
- Interaction
- Homodimer and homo-oligomer, interacts with GLRB, GABARAP, GABRA3, GLRB.
- Biology Area
- Cell Biology, Neuroscience, Neuroscience Cell Markers, Synaptic Biology
- Molecular Family
- Postsynaptic proteins
- Antigen References
-
- Alvarez FJ. 2017. Brain Res. Bull. 129:50.
- Tyagarajan SK, Fritschy JM. 2014. Nat. Rev. Neurosci. 15:141-56.
- Zacchi P, et al. 2014. Front Cell. Neurosci. 8:103.
- Gene ID
- 10243 View all products for this Gene ID 268566 View all products for this Gene ID 64845 View all products for this Gene ID
- UniProt
- View information about Gephyrin on UniProt.org
