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Purified anti-IDH1 Antibody
产品名称:
Purified anti-IDH1 Antibody
产品类别:
抗体
产品编号:
685302
产品应用:
685302
[价格]
规格 价格 库存
100µg ¥ 3710 1

产品详情

Product Details

Verified Reactivity
Human
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
Purified full length recombinant IDH1 expressed in 293T cells.
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.
Application

WB - Quality tested
KO/KD-WB, ICC - Verified

Recommended Usage

Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 0.5 - 2.0 ?g/ml. For immunocytochemistry, a concentration range of 1.0 - 5.0 μg/ml is recommended. It is recommended that the reagent be titrated for optimal performance for each application.

Application Notes

Does not react with mouse IDH1.

For immunofluorescence microscopy, positive staining was observed in the cytoplasm of HeLa cells.

RRID
AB_2616768 (BioLegend Cat. No. 685302)

Antigen Details

Structure
414 amino acids with the predicted molecular weight of approximately 47 kD.
Distribution

Cytoplasm and peroxisome.

Function
IDH1 enzyme plays an important role in lipid biosynthesis in different tissues such as the liver, adipose tissues, brain and tumors. Mutation of IDH is closely related to the progress and prognosis of certain tumors.
Interaction
Isocitrate
Biology Area
Cancer Biomarkers, Cell Biology
Antigen References

1. De Quintana-Schmidt C, et al. 2015. Neurocirugia (Astur.) 26:276.
2. Waitkus MS, et al. 2016. Neuro. Oncol. 18:16.
3. Liu X, et al. 2015. Histol. Histopathol. 30:1155.
4. Fathi AT, et al. 2015. Semin. Hematol. 52:165.
5. Vigneswaran K, et al. 2015. Ann. Transl. Med. 3:95.
6. Bogdanovic E. 2015. Biochim. Biophys. Acta. 1850(9):1781-5.
7. Parker SJ, et al. 2015. Pharmacol. Ther. 152:54.
8. Krell D, et al. 2013. Future Oncol. 9:1923.
9. McKenney AS, et al. 2013. J. Clin. Invest. 123:3672.

Gene ID
3417 View all products for this Gene ID
UniProt
View information about IDH1 on UniProt.org

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