Purified anti-SH2B3 (LNK) Antibody
- 产品名称：
- Purified anti-SH2B3 (LNK) Antibody
- 产品类别：
- 抗体
- 产品编号：
- 671101
- 产品应用：
- 671101
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Full-length recombinant human SH2B3 protein
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/mL
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
WB - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 0.1 - 1.0 ?g per ml. It is recommended that the reagent be titrated for optimal performance for each application.
- Application Notes
O92B11 was not tested for ICC or IP
- RRID
- AB_2814528 (BioLegend Cat. No. 671101) AB_2814529 (BioLegend Cat. No. 671102)
- Structure
- SH2B3/LNK is a 575 amino acid protein with a predicted molecular weight of 63 kDa
- Distribution
-
Cytoplasm, plasma membrane and nucleus/highly-expressed in hematopoietic cells
- Function
- Negative regulator of JAK/STAT pathway
- Cell Type
- Hematopoietic stem and progenitors
- Biology Area
- Signal Transduction
- Antigen References
-
- Oh ST, et al. 2010. Blood. 116:988.
- Perez-Garcia A, et al. 2013. Blood. 122:2425
- Lee S, et al. 2015. Oncotarget. 6:17764
- Ding LW, et al. 2019. Nat. Commun. 10:2230.
- Gene ID
- 10019 View all products for this Gene ID
- UniProt
- View information about SH2B3 on UniProt.org
