Purified anti-Tollip Antibody
- 产品名称：
- Purified anti-Tollip Antibody
- 产品类别：
- 抗体
- 产品编号：
- 854401
- 产品应用：
- 854401
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Full length human recombinant Tollip (NP_061882) produced in HEK293T cell.
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
WB - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 1.0 - 5.0 ?g per ml. It is recommended that the reagent be titrated for optimal performance for each application.
- Application Notes
This clone is highly specific to human Tollip. It does not cross react with murine Tollip.
- RRID
- AB_2750411 (BioLegend Cat. No. 854401) AB_2750472 (BioLegend Cat. No. 854402)
- Structure
- Tollip is a 274 amino acid protein with an apparent molecular mass of ~30 kD.
- Distribution
-
Tissue Distribution: Ubiquitously expressed.
Cellular Distribution: Plasma membrane, extracellular, cytosol, lysosome, and nucleus.
- Function
- Tollip is a component of the IL-1 and TLR signaling pathway involved in innate immune response.
- Interaction
- Tollip has been reported to interact with TOM1, TLR2, TLR4, IRAK1, IR-1RI, TOM1L2, and ILRAP.
- Biology Area
- Cell Biology, Immunology, Innate Immunity, Neurodegeneration, Neuroscience, Protein Trafficking and Clearance
- Molecular Family
- Enzymes and Regulators
- Antigen References
-
- Capelluto DG. 2012. Microbes Infect. 14(2): 140
- Brandao I, et al. 2015. Gut Microbes. 6(3):202
- Gene ID
- 54472 View all products for this Gene ID
- UniProt
- View information about Tollip on UniProt.org
