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Purified anti-SKIL (SnoN) Antibody
产品名称:
Purified anti-SKIL (SnoN) Antibody
产品类别:
抗体
产品编号:
644201
产品应用:
644201
[价格]
规格 价格 库存
25µg ¥ 1414 1

产品详情

Product Details

Verified Reactivity
Human
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
Partial human SKIL recombinant protein (307-684) produced in E. coli.
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/mL
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.
Application

WB -?Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 0.25 - 1.0 ?g per ml. It is recommended that the reagent be titrated for optimal performance for each application.

RRID
AB_2715795 (BioLegend Cat. No. 644201) AB_2715796 (BioLegend Cat. No. 644202)

Antigen Details

Structure
SKIL/SnoN is a 684 amino acid protein with a predicted molecular weight of 76.9 kDa.
Distribution

Nucleus

Function
SKIL functions as a transcriptional repressor when bound to the regulatory promoter region of TGFβ-responsive genes.
Interaction
SMAD2, SMAD3, RNF111, APC1, WWP1, RNF168, SMURF2
Biology Area
Cell Biology, Signal Transduction
Antigen References

1. Yin X,?et al.?2016.?Oncol Rep.?36:1535.
2.?Caligaris C,?et al.?2015.?Biochim. Biophys. Acta. 1850(9):1832.
3.?Annala M,?et al.?2015.?Oncotarget.?6:6235.
4. Ikeuchi Y,?et al.?2014.?J. Biol. Chem.?289: 25067.
5. Hagerstrand D,?et al.?2013.?Cancer Discover.?3: 1044.
6. Tsuneyoshi N, et al. 2012.?Genes Dev.?26: 2471.
7. Aarntzen EH,?et al.?2012.?Cancer Res.?72: 6102.
8. Zhang L,?et al.?2011.?J. Biol. Chem.?286: 10041.
9.?Stroschein SL,?et al.?2001.?Genes Dev.?15: 2822.?

Gene ID
6498 View all products for this Gene ID
UniProt
View information about SKIL on UniProt.org

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