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Purified anti-SIRT5 Antibody
产品名称:
Purified anti-SIRT5 Antibody
产品类别:
抗体
产品编号:
698801
产品应用:
698801
[价格]
规格 价格 库存
25µg ¥ 1414 1

产品详情

Product Details

Verified Reactivity
Human, Mouse
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
Full length protein expressed in 293T cell transfected with human SIRT5 expression vector.
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.
Application

WB -?Quality tested
KO/KD-WB - Verified

Recommended Usage

Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 0.2 - 2 ?g/mL. It is recommended that the reagent be titrated for optimal performance for each application.

Application Notes

SiRNA knockdown (KD) was used to confirm specificity of this antibody.

RRID
AB_2687321 (BioLegend Cat. No. 698801) AB_2687322 (BioLegend Cat. No. 698802)

Antigen Details

Structure
310 amino acids, and predicted Mw is 34kDa
Distribution

Mitochondrion

Function
NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically remove malonyl, succinyl and glutaryl groups on target proteins.
Interaction
Interacts with CPS1, cardiolipin. Forms homodimers upon suramin binding.
Biology Area
Cell Biology, Neuroscience, Neuroscience Cell Markers
Molecular Family
Mitochondrial Markers
Antigen References

1. Wegner M. 1999.?Nucleic Acids Res.?27: 1409.
2. Gertz M,?et al.?2016.?Cell. Mol. Life Sci.?73:2871.
3. Osborne B,?et al.?2016.?Free Radic. Biol. Med.?100:164.
4. Nakagawa T,?et al.?2009.?Cell?137:560.
5. Peng,?et al.?2011.?Mol. Cell. Proteomics?10:M111.012658.
6. Guan KL and Xiong Y. 2010.?Trends Biochem. Sci.?36: 108.
7. Rardin MJ,?et al.?2013.?Cell. Metab.?18:920.
8. Zhang Y,?et al.?2017.?J. Biol. Chem.?M117.785022.

Gene ID
23408 View all products for this Gene ID
UniProt
View information about SIRT5 on UniProt.org

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