Purified anti-UQCRC1 Antibody
- 产品名称：
- Purified anti-UQCRC1 Antibody
- 产品类别：
- 抗体
- 产品编号：
- 697601
- 产品应用：
- 697601
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Human recombinant protein fragment corresponding to amino acids 46-305 of human UQCRC1 expressed in E. Coli.
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
WB -?Quality tested
KO/KD-WB, ICC - Verified
- Recommended Usage
Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 0.1 - 1.0 ?g per ml. For immunocytochemistry, a concentration range of 0.5 - 5.0 μg/ml is recommended. It is recommended that the reagent be titrated for optimal performance for each application.
- Application Notes
This clone has very weak cross-reactivity with mouse UQCRC1.
Antibody specificity confirmed by partial knock-down of the target using siRNA (in-house tested).
- RRID
- AB_2687203 (BioLegend Cat. No. 697601) AB_2687187 (BioLegend Cat. No. 697602)
- Structure
- 480 amino acids, and predicted Mw is 52.6kDa.
- Distribution
-
Mitochondrion inner membrane
- Function
- Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain.
- Interaction
- The bc1 complex contains 11 subunits: 3 respiratory subunits (cytochrome b, cytochrome c1 and Rieske/UQCRFS1), 2 core proteins (UQCRC1/QCR1 and UQCRC2/QCR2) and 6 low-molecular weight proteins (UQCRH/QCR6, UQCRB/QCR7, UQCRQ/QCR8, UQCR10/QCR9, UQCR11/QCR10
- Biology Area
- Cell Biology, Mitochondrial Function, Neuroscience, Neuroscience Cell Markers, Protein Synthesis
- Molecular Family
- Mitochondrial Markers
- Antigen References
-
1. Ellinger J,?et al.?2016,?Oncotarget?7: 86490.
2.?Ma SL,?et al.?2016,?J. Psychiatr. Res.?76:143
- Gene ID
- 7384 View all products for this Gene ID
- UniProt
- View information about UQCRC1 on UniProt.org
