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Purified anti-MAFB Antibody
产品名称:
Purified anti-MAFB Antibody
产品类别:
抗体
产品编号:
692302
产品应用:
692302
[价格]
规格 价格 库存
25µg ¥ 1484 1

产品详情

Product Details

Verified Reactivity
Human
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
Recombinant human MAFB protein fragment produced in 293T cells.
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.
Application

WB - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 0.25 - 2.0 ?g per ml. It is recommended that the reagent be titrated for optimal performance for each application.

RRID
AB_2632763 (BioLegend Cat. No. 692302)

Antigen Details

Structure
323 amino acids with a predicted molecular weight of 36 kD.
Distribution

Nucleus

Function
Acts as a transcriptional activator or repressor. Plays a pivotal role in regulating lineage-specific hematopoiesis by repressing ETS1-mediated transcription of erythroid-specific genes in myeloid cells.
Interaction
Homodimer or heterodimer with other bHLH-Zip transcription factors. Binds DNA as a homodimer or a heterodimer. Forms homodimers and heterodimers with FOS, FOSB and FOSL2. Interacts with PAX6, ETS1 and LRP1.
Biology Area
Cell Biology, Transcription Factors
Antigen References

1. Kataoka K, et al. 1994. Mol. Cell. Biol. 14:700.
2. Eychene A, et al. 2008. Nat. Rev. Cancer 8:683.
3. Miyai M, et al. 2010. J. Dermatol. Sci. 57:178.
4. Suzuki K, et al. 2014. Proc. Natl. Acad. Sci. USA 111:16407.
5. Sarrazin S, et al. 2009. Cell. 138:300.
6. Vicente-Duenas C, et al. 2012. EMBO J. 31:3704.
7. Yang W, et al. 2015. BMC Cancer 15:461.
8. Yu H, et al. 2016. Cell. Physiol. Biochem. 39:700.

Gene ID
9935 View all products for this Gene ID
UniProt
View information about MAFB on UniProt.org

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