Purified anti-mouse CD146 Antibody
- 产品名称：
- Purified anti-mouse CD146 Antibody
- 产品类别：
- 抗体
- 产品编号：
- 134701
- 产品应用：
- 134701
- Verified Reactivity
- Mouse
- Antibody Type
- Monoclonal
- Host Species
- Rat
- Immunogen
- Endothelial cell line TME-3H3
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
FC - Quality tested
IHC-F - Verified
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 ?g per million cells in 100 ?l volume. For immunohistochemistry, a concentration range of 5.0 - 10.0 ?g/ml is suggested. It is recommended that the reagent be titrated for optimal performance for each application.
- Application References
(PubMed link indicates BioLegend citation) -
- Schrage A, et al. 2008. Histochem. Cell. Biol. 129:441.
- Birbrair A, et al. 2013. Am J Physiol Cell Physiol. 305:1098. PubMed
- Product Citations
-
- Weng L, et al. 2016. Sci Rep. 6:38632. PubMed
- Hirai M, et al. 2016. Circ Res . 118: 20 - 28. PubMed
- Hu X, et al. 2016. Nat Commun. 7:13095. PubMed
- Grosse L, et al. 2020. Cell Metabolism. 32(1):87-99.e6. PubMed
- Dane EL, et al. 2022. Nat Mater. 21:710. PubMed
- Chen L, et al. 2020. Front Immunol. 11:584458. PubMed
- Breitbach M, et al. 2018. Cell Stem Cell. 1.098611111. PubMed
- Lim PJ, et al. 2019. Nat Metab. 0.402083333. PubMed
- Tsuchimoto A, et al. 2020. Sci Rep. 10:10796. PubMed
- Mierzejewski B, et al. 2020. Stem Cell Res Ther. 0.695138889. PubMed
- Guimar?es‐Camboa N et al. 2017. Cell stem cell. 20(3):345-359 . PubMed
- Birbrair A, et al. 2013. Am J Physiol Cell Physiol. 305:1098. PubMed
- Qin XY, et al. 2017. EBioMedicine. 24:257. PubMed
- Prideaux M, et al. 2021. Sci Rep. 11:22593. PubMed
- Zhou H, et al. 2019. Genesis. :e23295. PubMed
- Luo Y, et al. 2017. Cell Res. 10.1038/cr.2017.8. PubMed
- RRID
- AB_1732002 (BioLegend Cat. No. 134701) AB_1731991 (BioLegend Cat. No. 134702)
- Structure
- CD146 is a transmembrane glycoprotein and belongs to the Ig superfamily of cell adhesion molecules.
- Distribution
-
CD146 is strongly expressed by murine vascular endothelial cells, a subset of NK1.1+ cells, and neutrophils.
- Function
- CD146 has been reported to be functionally relevant for endothelial cell adhesion, angiogenesis, and NK cell function.
- Ligand/Receptor
- Unidentified ligand.
- Cell Type
- Endothelial cells, Mesenchymal Stem Cells, Neutrophils
- Biology Area
- Cell Biology, Immunology, Neuroscience, Neuroscience Cell Markers, Stem Cells
- Molecular Family
- Adhesion Molecules, CD Molecules
- Antigen References
-
1. Despoix N, et al. 2008. Eur. J. Immunol. 38:2855.
2. Sorrentino A, et al. 2008. Exp. Hematol. 36:1035.
3. Bardin N, et al. 2009. Arterioscler. Thromb. Vasc. Biol. 29:746.
- Gene ID
- 84004 View all products for this Gene ID
- UniProt
- View information about CD146 on UniProt.org
