PE anti-mouse DcTRAIL-R1 Antibody
- 产品名称：
- PE anti-mouse DcTRAIL-R1 Antibody
- 产品类别：
- 抗体
- 产品编号：
- 133804
- 产品应用：
- 133804
- Verified Reactivity
- Mouse
- Antibody Type
- Monoclonal
- Host Species
- Armenian Hamster
- Immunogen
- mDcTRAIL-R1-Fc
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions.
- Concentration
- 0.2 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.25 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Excitation Laser
- Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
- Application References
(PubMed link indicates BioLegend citation) -
- Bareiss PM, et al. 2013. Cancer Res. 73:5544. PubMed
- Product Citations
-
- Knox T, et al. 2019. Sci Rep. 9:6136. PubMed
- Bareiss P, et al. 2013. Cancer Res. 73:5544. PubMed
- RRID
- AB_1626110 (BioLegend Cat. No. 133804)
- Structure
- GPI-anchored mouse TNF receptor super-family member that lacks a cytoplasmic death domain.
- Distribution
- Express on many types of cells, including some tumor cells.
- Function
- Appear to have a negative effect against TRAIL receptors because it lacks an intracellular death domain, and produces a competitive blockage of TRAIL-mediated apoptosis. The role of the DcR1 in apoptosis has not yet been clarified.
- Ligand/Receptor
- TRAIL
- Molecular Family
- Cytokine/Chemokine Receptors
- Antigen References
-
1. Yagyu S, et al. 2008. Clin Cancer Res. 14 (21):7011
2. Ashkenazi A, et al. 1998. Science 281:1305
- Gene ID
- 79201 View all products for this Gene ID
- UniProt
- View information about DcTRAIL R1 on UniProt.org
