Purified anti-human CD38 Antibody
- 产品名称：
- Purified anti-human CD38 Antibody
- 产品类别：
- 抗体
- 产品编号：
- 303502
- 产品应用：
- 303502
- Verified Reactivity
- Human
- Reported Reactivity
- Chimpanzee, Horse, Cow
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
FC - Quality tested
CyTOF? - Verified
IHC-F - Reported in the literature, not verified in house
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 2.0 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Application Notes
Additional reported applications (for the relevant formats) include: immunohistochemical staining of acetone-fixed frozen tissue sections6?and spatial biology (IBEX)10,11.
- Application References
(PubMed link indicates BioLegend citation) -
- Kishimoto T, et al. Eds. 1997. Leucocyte Typing VI. Garland Publishing Inc. London.
- Dieu M. 1998. J. Exp. Med. 188:373.
- Esser M, et al. 2001. J. Virol. 75:6173.
- Jeannin P, et al. 1999. J. Immunol. 162:2044.
- Kapsogeorgou EK, et al. 2001. J. Immunol. 166:3107.
- van der Voort R, et al. 1997. J. Exp. Med. 185:2121. (IHC)
- Bende RJ, et al. 2003. Am. J. Pathol. 162:105.
- Lehner M, et al. 2008. J. Leukoc. Biol. 83:883. PubMed
- Yoshino N, et al. 2000. Exp. Anim. (Tokyo) 49:97. (FC)
- Radtke AJ,?et al. 2020.?Proc Natl Acad Sci USA. 117:33455-33465. (SB)?PubMed
- Radtke AJ,?et al. 2022.?Nat Protoc. 17:378-401. (SB)?PubMed
- Product Citations
-
- Tornack J, et al. 2017. PLoS One. 12:e0169119. PubMed
- Rouers A, et al. 2021. Cell Rep Med. 2:100278. PubMed
- Meckiff BJ, et al. 2019. J Immunol. 203:1276. PubMed
- Friebel E, et al. 2020. Cell. 181(7):1626-1642.e20. PubMed
- Wagner J et al. 2019. Cell. 177(5):1330-1345 . PubMed
- Stras SF, et al. 2020. Developmental Cell. 51(3):357-373.e5.. PubMed
- Sullivan KD, et al. 2021. Cell Reports. 36(7):109527. PubMed
- Chakhtoura M, et al. 2021. PLoS Pathog. 17:e1009732. PubMed
- Mann ER, et al. 2020. Sci Immunol. :5. PubMed
- Kaufmann M, et al. 2021. Med. 2(3):296-312.e8. PubMed
- Roukens AHE, et al. 2022. Nat Immunol. 23:23. PubMed
- Vivanco Gonzalez N, et al. 2022. STAR Protoc. 3:101280. PubMed
- Kondo H, et al. 2022. Front Immunol. 13:836923. PubMed
- Syrimi E, et al. 2021. iScience. 24:103215. PubMed
- O'Boyle KC, et al. 2020. Methods Mol Biol. 2111:1. PubMed
- Olin A, et al. 2018. Cell. 174:1277. PubMed
- Galbraith MD, et al. 2021. eLife. 10:00. PubMed
- Wastyk HC, et al. 2021. Cell. 184(16):4137-4153.e14. PubMed
- Baskar R, et al. 2022. Cell Rep Methods. 2:. PubMed
- Eccles JD, et al. 2020. Cell Rep. 30:351. PubMed
- Han L, et al. 2019. Haematologica. 10.3324/haematol.2018.205534. PubMed
- Gee MH, et al. 2018. Cell. 172:549. PubMed
- Chng MHY, et al. 2020. Immunity. 51(6):1119-1135.e5.. PubMed
- Henrick BM, et al. 2021. Cell. . PubMed
- Roussel M, et al. 2021. Cell Reports Medicine. 2(6):100291. PubMed
- Newell KL, et al. 2021. PLoS One. 16:e0244855. PubMed
- Evrard M et al. 2018. Immunity. 48(2):364-379 . PubMed
- NULL, et al. 2022. Cell. 185:916. PubMed
- Zhou H, et al. 2017. Leukemia. 31:2065. PubMed
- Baum N, et al. 2020. Cancers (Basel). 13:. PubMed
- Chevrier S, et al. 2021. Cell Reports Medicine. 2(1):100166. PubMed
- Stensland ZC, et al. 2022. iScience. 25:103626. PubMed
- Crawford LB, et al. 2021. J Virol. 95:. PubMed
- Li Z, et al. 2020. J Clin Lab Anal. 34:e23155. PubMed
- Chiou SH, et al. 2021. Immunity. 54:586. PubMed
- RRID
- AB_314354 (BioLegend Cat. No. 303502)
- Structure
- ADP-ribosyl cyclase, ectoenzyme, type II glycoprotein, 45 kD
- Distribution
-
T cells, B cells, NK, myeloid, plasma, and dendritic cells
- Function
- Ecto-ADP-ribosyl cyclase, calcium signaling, cell activation
- Ligand/Receptor
- CD31, hyaluronic acid
- Cell Type
- B cells, Dendritic cells, NK cells, Plasma cells, T cells
- Biology Area
- Immunology
- Molecular Family
- Adhesion Molecules, CD Molecules
- Antigen References
-
1. Ferrero E, et al. 1999. J. Leukoc. Biol. 65:151.
2. Lund F, et al. 1995. Immunol. Today 16:469.
- Gene ID
- 952 View all products for this Gene ID
- UniProt
- View information about CD38 on UniProt.org
