Brilliant Violet 421™ anti-human CD42b Antib
- 产品名称：
- Brilliant Violet 421™ anti-human CD42b Antib
- 产品类别：
- 抗体
- 产品编号：
- 303929
- 产品应用：
- 303929
[价格]
| 规格 |
价格 |
库存 |
| 25tests |
￥ 2310 |
1 |
- Verified Reactivity
- Human
- Reported Reactivity
- Chimpanzee
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA).
- Preparation
- The antibody was purified by affinity chromatography and conjugated with Brilliant Violet 421? under optimal conditions.
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.
Brilliant Violet 421? excites at 405 nm and emits at 421 nm. The standard bandpass filter 450/50 nm is recommended for detection. Brilliant Violet 421? is a trademark of Sirigen Group Ltd.
Learn more about Brilliant Violet?.
This product is subject to proprietary rights of Sirigen Inc. and is made and sold under license from Sirigen Inc. The purchase of this product conveys to the buyer a non-transferable right to use the purchased product for research purposes only. This product may not be resold or incorporated in any manner into another product for resale. Any use for therapeutics or diagnostics is strictly prohibited. This product is covered by U.S. Patent(s), pending patent applications and foreign equivalents. - Excitation Laser
- Violet Laser (405 nm)
- Application Notes
Clone HIP1 recognizes an epitope within the N-terminal region of the GPIba chain5. Additional reported applications (for the relevant formats) include: immunohistochemical staining of acetone-fixed frozen tissue sections, Westerm blotting, and inhibition of platelet aggregation2. The Ultra LEAF? purified antibody (Endotoxin < 0.01 EU/?g, Azide-Free, 0.2 ?m filtered) is recommended for functional assays (Cat. No. 303939).
- Application References
(PubMed link indicates BioLegend citation) -
- Knapp W, et al. 1989. Leucocyte Typing IV. Oxford University Press. New York.
- Takahashi R, et al. 1999. Blood. 93:1951.
- Saggu G, et al. 2013. J. Immunol. 190:6457. PubMed
- Meyer Dos Santos S, et al. 2011. Blood. 117:4999. (Block) PubMed
- Vettore S, et al. 2008. Haematologica. 93:1743.
- Product Citations
-
- Baumer Y, et al. 2020. J Transl Med. 18:29. PubMed
- RRID
- AB_2715930 (BioLegend Cat. No. 303929) AB_2715931 (BioLegend Cat. No. 303930)
- Structure
- Mucin, leucine-rich repeat family, 145 kD
- Distribution
-
Platelets, megakaryocytes
- Function
- Complex with CD42a, c and d, platelet adhesion and activation
- Ligand/Receptor
- Von Willebrand factor, thrombin
- Cell Type
- Megakaryocytes, Platelets
- Biology Area
- Cell Adhesion, Cell Biology, Immunology
- Molecular Family
- Adhesion Molecules, CD Molecules
- Antigen References
-
1. Clemetson K, et al. 1982. J. Clin. Invest. 70:304.
2. Fox J, et al. 1988. J. Biol. Chem. 263:4882.
3. Kuijpers R, et al. 1992 Blood 79:283.
- Gene ID
- 2812 View all products for this Gene ID
- UniProt
- View information about CD42b on UniProt.org
