GMP APC anti-human CD19 Antibody
- 产品名称：
- GMP APC anti-human CD19 Antibody
- 产品类别：
- 抗体
- 产品编号：
- 260058
- 产品应用：
- 260058
[价格]
| 规格 |
价格 |
库存 |
| 100tests |
￥ 4858 |
1 |
- Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide, 0.2% (w/v) BSA (origin USA) and a stabilizer.
- Preparation
- The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions.
- Concentration
- 50 ?g/mL
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?L per million cells in 100 ?L staining volume or 5 ?L per 100 ?L of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
- Excitation Laser
- Red Laser (633 nm)
- Application Notes
Additional reported applications (for the relevant formats) include: immunohistochemical staining of acetone-fixed frozen tissue sections8 and blocking of B cell proliferation. Clone HIB19 is not recommended for formalin-fixed paraffin-embedded sections. The Ultra-LEAF? purified antibody (Endotoxin < 0.01 EU/?g, Azide-Free, 0.2 ?m filtered) is recommended for functional assays (Cat. No. 302267 & 302268).
- Application References
(PubMed link indicates BioLegend citation) -
- Schlossman S,?et al.?1995. Leucocyte Typing V. Oxford University Press. New York.
- Knapp W,?et al.?1989. Leucocyte Typing IV. Oxford University Press. New York.
- Bradbury L,?et al.?1993.?J. Immunol.?151:2915.
- Joseph A,?et al.?2010.?J. Virol.?84:6645.?PubMed
- Wang X,?et al.?2010.?Haematologica.?95:884. (FC)?PubMed
- Walker JD,?et al.?2009.?J. Immunol.?182:1548. (Block)?PubMed
- Yoshino N,?et al.?2000.?Exp. Anim. (Tokyo)?49:97. (FC)
- Hansen A,?et al.?2002.?Arthritis Rheum.?46:2160. (IHC)
- Stoeckius M, et al. 2017. Nat. Methods. 14:865. (PG)
- Peterson VM, et al. 2017. Nat. Biotechnol. 35:936. (PG)
- RRID
- AB_2910364 (BioLegend Cat. No. 260058)
- Disclaimer
GMP RUO Flow Cytometry Antibodies. BioLegend GMP RUO fluorophore conjugated antibodies are manufactured in a dedicated GMP facility and?compliant with ISO 13485:2016. For research use only. Not for use in diagnostic or therapeutic procedures. Our processes include:?
- Batch-to-batch consistency
- Material traceability
- Documented procedures
- Documented employee training
- Equipment maintenance and monitoring records
- Lot-specific certificates of analysis
- Quality audits per ISO 13485:2016
- QA review of released products
?
- Structure
- Ig superfamily, type I transmembrane glycoprotein, 95 kD
- Distribution
-
B lineage (except plasma cells), follicular dendritic cells
- Function
- B cell activation and differentiation
- Ligand/Receptor
- Forms complex with CD21 (CR2) and CD81 (TAPA-1), BCR coreceptor
- Cell Type
- B cells, Dendritic cells
- Biology Area
- Costimulatory Molecules, Immunology
- Molecular Family
- CD Molecules
- Antigen References
-
- Tedder T, et al. 1994. Immunol?Today. 15:437-42.
- Bradbury L, et al. 1993. J?Immunol. 151:2915-27.
- Gene ID
- 930 View all products for this Gene ID
- UniProt
- View information about CD19 on UniProt.org
