热线电话: 021-34661275
产品分类/PRODUCT CLASSIFICATION

上海细胞库

人源细胞系| 稳转细胞系| 基因敲除株| 基因点突变细胞株| 基因过表达细胞株| 重组细胞系| 猪的细胞系| 马细胞系| 兔的细胞系| 犬的细胞系| 山羊的细胞系| 鱼的细胞系| 猴的细胞系| 仓鼠的细胞系| 狗的细胞系| 牛的细胞| 大鼠细胞系| 小鼠细胞系| 其他细胞系|

原代细胞

原代细胞| 永生化细胞|

细胞培养

血清| 无血清冻存| 细胞培养试剂盒| 普通培养基| 完全培养基| 细胞污染预防| 细胞污染清除| 细胞培养辅助试剂|

细胞服务

STR鉴定服务| ATCC代购服务|

酶联试剂盒

人ELISA试剂盒| 大鼠ELISA试剂盒| 小鼠ELISA试剂盒| 兔ELISA试剂盒| 猪ELISA试剂盒| 鱼ELISA试剂盒| 牛ELISA试剂盒| 犬ELISA试剂盒| 鸭ELISA试剂盒| 豚鼠ELISA试剂盒| 鸡ELISA试剂盒| 绵羊ELISA试剂盒| 山羊ELISA试剂盒| 仓鼠ELISA试剂盒| 植物ELISA试剂盒| 药残留类试剂盒| 其他ELISA试剂盒|

生化试剂盒

生化试剂盒| 微量法检测盒| 分光法检测盒| 胶体金检测盒|

PCR试剂盒

荧光探针PCR试剂盒| 染料荧光PCR试剂盒| 核酸扩增/纯化| 普通PCR检测试剂盒| 质粒菌种感受态|

抗体蛋白

蛋白多肽| 抗体| 免疫组化| 免疫球蛋白|

试剂耗材

标准试液| 科研试剂| 缓 冲 液| 实验耗材| 高效液相色谱对照品|

首页 > 抗体蛋白 > 抗体
FITC anti-human CD19 Antibody
产品名称：
FITC anti-human CD19 Antibody
产品类别：
抗体
产品编号：
302205
产品应用：
302205
[价格]
规格 价格 库存
25tests ￥ 700 1

产品详情

Product Details

Verified Reactivity
Human
Reported Reactivity
Chimpanzee
Antibody Type
Monoclonal
Host Species
Mouse
Formulation
?g size: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
test sizes: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA).
Preparation
The antibody was purified by affinity chromatography, and conjugated with FITC under optimal conditions.
Concentration
?g sizes: 0.5 mg/mL
test sizes: lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining using the ?g size, the suggested use of this reagent is ≤1.0 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application. For flow cytometric staining using the test sizes, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.

Excitation Laser
Blue Laser (488 nm)
Application Notes

Additional reported applications (for the relevant formats) include: immunohistochemical staining of acetone-fixed frozen tissue sections8 and blocking of B cell proliferation. Clone HIB19 is not recommended for formalin-fixed paraffin-embedded sections. The Ultra-LEAF? purified antibody (Endotoxin < 0.01 EU/?g, Azide-Free, 0.2 ?m filtered) is recommended for functional assays (Cat. No. 302267 & 302268).

?

Clone HIB19 partially blocks anti-human CD19 clones 4G7 and SJ25C1 staining based on in-house testing

Application References

(PubMed link indicates BioLegend citation)
  1. Schlossman S, et al. 1995. Leucocyte Typing V. Oxford University Press. New York.
  2. Knapp W, et al. 1989. Leucocyte Typing IV. Oxford University Press. New York.
  3. Bradbury L, et al. 1993. J. Immunol. 151:2915.
  4. Joseph A, et al. 2010. J. Virol. 84:6645. PubMed
  5. Wang X, et al. 2010. Haematologica. 95:884. (FC) PubMed
  6. Walker JD, et al. 2009. J. Immunol. 182:1548. (Block) PubMed
  7. Yoshino N, et al. 2000. Exp. Anim. (Tokyo) 49:97. (FC)
  8. Hansen A, et al. 2002. Arthritis Rheum. 46:2160. (IHC)
  9. Stoeckius M, et al. 2017. Nat. Methods. 14:865. (PG)
  10. Peterson VM, et al. 2017. Nat. Biotechnol. 35:936. (PG)
Product Citations
  1. Toepfner N et al. 2018. eLife. 7 pii: e29213. PubMed
  2. Kuri-Maga?a H, et al. 2018. Front Immunol. 9:2679. PubMed
  3. Chabi S, et al. 2020. Cell Reports. 29(8):2307-2320.e6.. PubMed
  4. Muto M, et al. 2016. J Am Soc Nephrol. 10.1681/ASN.2016050496. PubMed
  5. Rosa TLSA, et al. 2022. Front Med (Lausanne). 9:899998. PubMed
  6. Hagan T, et al. 2020. Cell. 178(6):1313-1328.e13.. PubMed
  7. Kerr SC, et al. 2020. Clin Exp Allergy. 50:904. PubMed
  8. Hess NJ, et al. 2020. J Immunol. 205:272. PubMed
  9. Kaku Y, et al. 2021. Cell Reports. 36(2):109385. PubMed
  10. Laustsen A, et al. 2021. Elife. 10:. PubMed
  11. Lefley D, et al. 2019. Breast Cancer Res. 0.965277778. PubMed
  12. Jama B, Morris G 2014. J Vis Exp. 93: 52257. PubMed
  13. Esaulova E, et al. 2020. Cell Host Microbe. 29(2):165-178.e8. PubMed
  14. Wurzer H, et al. 2021. Front Immunol. 12:619069. PubMed
  15. Liu C, et al. 2021. Cell Res. 31:1106. PubMed
  16. Halim L, et al. 2022. Front Immunol. 13:836549. PubMed
  17. Scherer SD, et al. 2021. Breast Cancer Res. 23:100. PubMed
  18. Hansen IS, et al. 2018. Nat Commun. 9:863. PubMed
  19. Aravena O, et al. 2017. Arthritis Res Ther. 19:8. PubMed
  20. Wang X, et al. 2010. Haematologica. 95:884. PubMed
  21. Yang R, et al. 2020. Cell. 183(7):1826-1847.e31. PubMed
  22. Mu Z, et al. 2021. Genome Biol. 122:22. PubMed
  23. Jing Y, et al. 2021. Signal Transduct Target Ther. 6:345. PubMed
  24. Zhang J, et al. 2022. Nature. 609:369. PubMed
  25. Brown CC, et al. 2020. Cell. 179(4):846-863.e24.. PubMed
  26. , et al. 2021. Eur J Immunol. 51:2708. PubMed
  27. Wang F, et al. 2021. Cell. 184(2):422-440.e17. PubMed
  28. Hazenberg MD, et al. 2019. Blood Adv. 2.659722222. PubMed
  29. Janela B, et al. 2019. Immunity. 50:1069. PubMed
  30. Cheng Y, et al. 2021. Immunity. 54(8):1825-1840.e7. PubMed
  31. Krishnan S, et al. 2021. Clin Exp Immunol. 203:458. PubMed
  32. Lu J, et al. 2021. Front Immunol. 12:732612. PubMed
  33. Valle-Reyes S, et al. 2020. Cell Physiol Biochem. 54:842. PubMed
  34. Golebski K, et al. 2021. Immunity. 54(2):291-307.e7. PubMed
  35. Motwani MP, et al. 2018. JCI Insight. 3:e94463. PubMed
  36. Mishra A, et al. 2021. Cell. 184(13):3394-3409.e20. PubMed
  37. Bradley D, et al. 2022. Nat Commun. 13:5606. PubMed
  38. Hu Q, et al. 2021. Nat Commun. 12:2186. PubMed
  39. Zegarra‐Ruiz DF et al. 2018. Cell host & microbe. 25(1):113-127 . PubMed
  40. ?yszkiewicz M, et al. 2020. Nat Commun. 11:1031. PubMed
  41. Bal S, et al. 2016. Nat Immunol. 10.1038/ni.3444. PubMed
  42. Buters TP, et al. 2021. Br J Clin Pharmacol. Online ahead of print. PubMed
  43. Wang F, et al. 2021. Genomics Proteomics Bioinformatics. 19:208. PubMed
  44. Ruan Y, et al. 2022. Exp Ther Med. 23:47. PubMed
  45. Foote JR, et al. 2019. Front Immunol. 10:188. PubMed
  46. Beyer AI, et al. 2017. Stem Cells Dev. 26:102. PubMed
  47. Kwok I, et al. 2020. Immunity. 53(2):303-318.e5. PubMed
  48. Lavaert M, et al. 2020. Frontiers in Immunology. 1.610416667. PubMed
  49. Chen YP, et al. 2020. Cell Res. 30:1024. PubMed
  50. Wells DK, et al. 2020. Cell. 183:818. PubMed
  51. Lareau CA, et al. 2020. Nat Biotechnol. 39:451. PubMed
  52. Rusconi M, et al. 2017. Sci Rep. 5.745138889. PubMed
  53. Dinh HQ, et al. 2020. Immunity. 53(2):319-334.e6. PubMed
  54. Wang SQ, et al. 2021. J Viral Hepat. 28:795. PubMed
  55. Du Z, et al. 2020. J Allergy Clin Immunol. . PubMed
  56. Lepore M, et al. 2014. J Exp Med. 211:1363. PubMed
RRID
AB_314235 (BioLegend Cat. No. 302205) AB_314236 (BioLegend Cat. No. 302206) AB_2564143 (BioLegend Cat. No. 302256)

Antigen Details

Structure
Ig superfamily, type I transmembrane glycoprotein, 95 kD
Distribution

B lineage (except plasma cells), follicular dendritic cells

Function
B cell activation and differentiation
Ligand/Receptor
Forms complex with CD21 (CR2) and CD81 (TAPA-1), BCR coreceptor
Cell Type
B cells, Dendritic cells
Biology Area
Costimulatory Molecules, Immunology
Molecular Family
CD Molecules
Antigen References

1. Tedder T, et al. 1994. Immunol. Today 15:437.
2. Bradbury L, et al. 1993. J. Immunol. 151:2915.

Gene ID
930 View all products for this Gene ID
UniProt
View information about CD19 on UniProt.org

联系我们

TEL：021-34661275 　点击拨打热线