Alexa Fluor® 594 anti-mouse CD37 Antibody
- 产品名称:
- Alexa Fluor® 594 anti-mouse CD37 Antibody
- 产品类别:
- 抗体
- 产品编号:
- 146206
- 产品应用:
- 146206
- Verified Reactivity
- Mouse
- Antibody Type
- Monoclonal
- Host Species
- Rat
- Immunogen
- Expression vector containing full length mouse CD37 gene
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography and conjugated with Alexa Fluor? 594 under optimal conditions.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
IHC-F - Quality tested
3D IHC - Verified
- Recommended Usage
Each lot of this antibody is quality control tested by immunohistochemical staining on frozen tissue sections. For immunohistochemistry, a concentration range of 2.5 - 10 ?g/ml is suggested. For 3D immunohistochemistry on formalin-fixed tissues, a concentration of 5.0 ?g/mL is suggested. It is recommended that the reagent be titrated for optimal performance for each application.
* Alexa Fluor? 594 has an excitation maximum of 590 nm, and a maximum emission of 617 nm.
Alexa Fluor? and Pacific Blue? are trademarks of Life Technologies Corporation.
View full statement regarding label licenses - RRID
- AB_2632758 (BioLegend Cat. No. 146206)
- Structure
- Member of the tetraspanin (TM4SF) family, with two extracellular regions, both termini are cytoplasmic, 40-60 kD
- Distribution
-
Highly expressed on B cells, low expression on T cells, monocytes, macrophages, neutrophils, and dendritic cells
- Function
- Essential for B cell survival, regulates T cell proliferation, regulates IgA production, involved in dendritic cell migration
- Cell Type
- B cells, Dendritic cells, Neutrophils
- Biology Area
- Costimulatory Molecules, Immunology, Innate Immunity
- Molecular Family
- CD Molecules
- Antigen References
-
1. Gartlan KH, et al. 2013. Eur. J. Immunol. 43:1208.
2. Annemiek B, et al. 2012. Sci. Signal. 5:82.
3. van Spriel AB. 2011. Biochem. Soc. Trans. 39:512.
4. Heider, KH, et al. 2012. Blood 118:4159.
- Gene ID
- 12493 View all products for this Gene ID
- UniProt
- View information about CD37 on UniProt.org