Alexa Fluor® 647 anti-mouse CD39 Antibody
- 产品名称：
- Alexa Fluor® 647 anti-mouse CD39 Antibody
- 产品类别：
- 抗体
- 产品编号：
- 143807
- 产品应用：
- 143807
- Verified Reactivity
- Mouse
- Antibody Type
- Monoclonal
- Host Species
- Rat
- Immunogen
- CD39 cDNA expression vector
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography and conjugated with Alexa Fluor? 647 under optimal conditions.
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤2.0 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.
* Alexa Fluor? 647 has a maximum emission of 668 nm when it is excited at 633 nm / 635 nm.
Alexa Fluor? and Pacific Blue? are trademarks of Life Technologies Corporation.
View full statement regarding label licenses - Excitation Laser
- Red Laser (633 nm)
- Product Citations
-
- Miska J et al. 2019. Cell reports. 27(1):226-237 . PubMed
- Medina CB, et al. 2021. Immunity. 54(8):1715-1727.e7. PubMed
- Sade–Feldman M, et al. 2018. Cell. 175:998. PubMed
- RRID
- AB_2563977 (BioLegend Cat. No. 143807) AB_2563978 (BioLegend Cat. No. 143808)
- Structure
- A member of ectonucleoside triphosphate dihydrolases (E-NTPDases), an ectoenzyme that degrades ATP to AMP
- Distribution
-
B cells, dendritic cells, and a subset of T cells
- Function
- Involved in suppression of inflammation and control of platelet activation; coordinated expression of CD39/CD73 on Tregs and the adenosine A2A receptor on activated T effector cells generates immunosuppressive loops
- Interaction
- Proteolysis of amyloid precursor protein (APP)
- Cell Type
- B cells, Dendritic cells, T cells, Tregs
- Biology Area
- Immunology
- Molecular Family
- CD Molecules
- Antigen References
-
1. Borsellino G, et al. 2007. Blood 110:1225.
2. Deaglio S, et al. 2007. J. Exp. Med. 204:1257.
3. Bynoe MS, et al. 2008. Trends Immunol. 29:99.
4. Ndhlovu LC, et al. 2010. Eur. J. Immunol. 40:134.
- Gene ID
- 12495 View all products for this Gene ID
- UniProt
- View information about CD39 on UniProt.org
