Purified anti-Desmoglein 3 Antibody
- 产品名称：
- Purified anti-Desmoglein 3 Antibody
- 产品类别：
- 抗体
- 产品编号：
- 871901
- 产品应用：
- 871901
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/mL
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
WB -?Quality tested
ICC -?Verified
- Recommended Usage
Each lot of this antibody is quality control tested by western blotting. For western blotting, the suggested use of this reagent is 0.5?- 1.0??g/mL.?For immunocytochemistry, a concentration range of 2.0?- 10?μg/mL is recommended. It is recommended that the reagent be titrated for optimal performance for each application.
- Application References
(PubMed link indicates BioLegend citation) -
- Wan H, et al. 2016. Data Brief. 6:124-34 (WB, ICC)
- Walter E,?et al.?2017.?Sci Rep. 7:3579 (ICC)
- Tsang SM, et al. 2010. PloS One. 5:e14211 (WB, ICC)
- RRID
- AB_2876750 (BioLegend Cat. No. 871901) AB_2876750 (BioLegend Cat. No. 871902)
- Structure
- Desmoglein 3 is a 999 amino acid protein with predicted molecular mass of 108 kD and observed molecular mass of ~130 kD.
- Distribution
-
Tissue Distribution: Esophagus, skin, tonsil
Cellular Distribution: Plasma membrane, cytosol, extracellular
- Function
- Desmoglein-3 is the Ca2+ binding transmembrane components of the desmosomes that functions as cell-cell junctions between epithelial cells as well as other cell types.
- Interaction
- PKP3, JUP, WWOX, FRMD1, OAZ3
- Cell Type
- Endothelial cells, Epithelial cells
- Biology Area
- Adaptive Immunity, Neurodegeneration, Neuroinflammation, Neuroscience, Neuroscience Cell Markers, Signal Transduction
- Molecular Family
- Adhesion Molecules, Gap Junction Proteins
- Antigen References
-
- Mahmoudi H, et al. 2020. Int J Immunogenet. 47:41-9
- Spindler V & Waschke J. 2018. Front immunol. 9:136
- Pan M, et al.?2015.?J Dermatol. 42:11-7
- Gene ID
- 1830 View all products for this Gene ID
- UniProt
- View information about Desmoglein 3 on UniProt.org
