PE anti-human DcR1 (TRAIL-R3, CD263) Antibody
- 产品名称：
- PE anti-human DcR1 (TRAIL-R3, CD263) Antibody
- 产品类别：
- 抗体
- 产品编号：
- 307005
- 产品应用：
- 307005
[价格]
| 规格 |
价格 |
库存 |
| 25tests |
￥ 1974 |
1 |
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Extracellular domain of DcR1-human IgG1 Fc fusion protein
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.
- Excitation Laser
- Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
- Application Notes
Additional reported applications (for the relevant formats) include: The DJR3 antibody is useful for immunofluorescent staining and flow cytometric analysis of DcR1/TRAIL-R3 receptor expression. For most successful immunofluorescent staining results, it may be important to maximize signal over background by using a relatively bright fluorochrome-antibody conjugate (Cat. No. 307006) or by using a high sensitivity, three-layer staining technique (e.g., including a biotinylated antibody (Cat. No. 307004) or biotinylated anti-mouse IgG second step (Cat. No. 405303), followed by SAv-PE (Cat. No. 405204)).
- Application References
(PubMed link indicates BioLegend citation) -
- Uno K, et al. 2003. Blood 101:3658.
- Sato K, et al. 2005. J. Immunol. 174:4025.
- Product Citations
-
- Greenlee JD, et al. 2021. eLife. 0.416666666666667. PubMed
- Chen QZ, et al. 2020. Front Immunol. 1.202777778. PubMed
- Staniek J, et al. 2019. Front Immunol. 10:951. PubMed
- RRID
- AB_2287506 (BioLegend Cat. No. 307005) AB_2205089 (BioLegend Cat. No. 307006)
- Structure
- TNFR superfamily, GPI-anchored, truncated death domain, 65 kD
- Distribution
-
Most normal tissues, not tumors
- Function
- TRAIL decoy, inhibits apoptosis
- Ligand/Receptor
- TRAIL
- Biology Area
- Apoptosis/Tumor Suppressors/Cell Death, Cell Biology, Immunology
- Molecular Family
- CD Molecules, Cytokine/Chemokine Receptors
- Antigen References
-
1. Schneider P, et al. 1997. J. Biol. Chem. 272:25417.
2. Pan G, et al. 1997. Science 277:815.
- Gene ID
- 8794 View all products for this Gene ID
- UniProt
- View information about CD263 on UniProt.org
