Purified anti-SMC3 Antibody
- 产品名称：
- Purified anti-SMC3 Antibody
- 产品类别：
- 抗体
- 产品编号：
- 605351
- 产品应用：
- 605351
- Verified Reactivity
- X. laevis (reported)
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Synthetic fragment of X. laevis SMC3, raised from mice immunized with the peptide sequence: EEVSLRRVIGAKKDQYFLDKK, corresponding to amino acids 94 -114 of Xenopus laevis SMC3.
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/mL
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
WB - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by western blotting. For western blotting, the suggested use of this reagent is 0.25 - 1.0??g/mL. It is recommended that the reagent be titrated for optimal performance for each application.
- Application Notes
Product was tested for use in ICC and IHC-P applications but did not meet passing criteria.
- RRID
- AB_2924611 (BioLegend Cat. No. 605351) AB_2924611 (BioLegend Cat. No. 605352)
- Structure
- SMC3 is a 1217 amino acid protein with a predicted molecular weight of 141.5 kD.
- Distribution
-
SMC3 is present in the nucleus of cells. During mitosis, it segregates exclusively at the centrosomes of chromosomes.?
- Interaction
- SMC3 is a component of the cohesion complex consisting SMC1, SCC1, and SCC3
- Biology Area
- Cell Biology, Cell Cycle/DNA Replication
- Antigen References
-
- Beckouet F, et al. 2010. Mol?Cell. 39:689-99.?
- Boyle MI, et al. 2015. Clin?Genet. 88:1-12.?
- Gligoris TG, et al. 2014. Science. 346:963-7.?
- Gene ID
- 9126 View all products for this Gene ID
- UniProt
- View information about SMC3 on UniProt.org
