Purified anti-mouse IL-33Rα (IL1RL1, ST2) An
- 产品名称：
- Purified anti-mouse IL-33Rα (IL1RL1, ST2) An
- 产品类别：
- 抗体
- 产品编号：
- 145301
- 产品应用：
- 145301
- Verified Reactivity
- Mouse
- Antibody Type
- Monoclonal
- Host Species
- Rat
- Immunogen
- IL-33Rα-hFcγ1 fusion protein.
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.25 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Application References
(PubMed link indicates BioLegend citation) -
- Hashiguchi M, et al. 2014. Eur. J. Immunology. (FC) PubMed
- Product Citations
-
- Chudnovskiy A et al. 2016. Cell. 167(2):444-456 . PubMed
- Matsuba S, et al. 2017. Front Immunol. . 10.3389/fimmu.2017.01538. PubMed
- Schuler CF, et al. 2020. Allergy. 75:2279. PubMed
- Yates K, et al. 2018. Proc Natl Acad Sci U S A. 115:2162. PubMed
- RRID
- AB_2561842 (BioLegend Cat. No. 145301) AB_2561843 (BioLegend Cat. No. 145302)
- Structure
- 63 kD, IL-1 receptor family member, single pass type I membrane protein
- Distribution
-
Mast cells, Th2 cells, and fibroblasts
- Function
- Following interaction with IL-33, it recruits MyD88, Irak1, Irak4 and Traf6 followed by phosphorylation of the MAP/ERK pathway.
- Interaction
- Interacts with MyD88, Irak1, Irak4 and Traf6
- Ligand/Receptor
- IL-33
- Cell Type
- Fibroblasts, Mast cells, Th2
- Biology Area
- Immunology, Innate Immunity
- Molecular Family
- Cytokine/Chemokine Receptors
- Antigen References
-
1. Yanagisawa K, et al. 1993. FEBS Lett. 318:83.
2. Schmitt E, et al. 1990. Cytokine 6:407.
3. Yanagisawa K, et al. 1992. FEBS Lett. 302:51.
4. Takagi T, et al. 1993. Biochim Biophys Acta. 1178:194.
- Gene ID
- 17082 View all products for this Gene ID
- UniProt
- View information about IL-33Ralpha on UniProt.org
