PE anti-mouse IL-33Rα (IL1RL1, ST2) Antibody
- 产品名称：
- PE anti-mouse IL-33Rα (IL1RL1, ST2) Antibody
- 产品类别：
- 抗体
- 产品编号：
- 145303
- 产品应用：
- 145303
- Verified Reactivity
- Mouse
- Antibody Type
- Monoclonal
- Host Species
- Rat
- Immunogen
- IL-33Rα-hFcγ1 fusion protein.
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.
- Concentration
- 0.2 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤1.0 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Excitation Laser
- Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
- Application References
(PubMed link indicates BioLegend citation) -
- Hashiguchi M, et al. 2014. Eur. J. Immunology. (FC) PubMed
- Product Citations
-
- Furuhashi K, et al. 2017. Immunology. 151:227. PubMed
- Karagiannis F, et al. 2020. Immunity. 52(4):620-634. PubMed
- Wang L, et al. 2019. Cell Rep. 29:1848. PubMed
- Shani O, et al. 2020. Cancer Res. 80:5317. PubMed
- Delacher M, et al. 2021. Immunity. 54(4):702-720.e17. PubMed
- She L, et al. 2021. JCI Insight. 6:e143509. PubMed
- Wu G, et al. 2020. Br J Pharmacol. 177:5063. PubMed
- Wiesner D, et al. 2015. PLoS Pathog. 11:1004701. PubMed
- He J, et al. 2020. Cell Reports. 29(9):2718-2730.e6.. PubMed
- Nakajima T, et al. 2021. J Exp Med. 218:. PubMed
- Xi‐Zhi J Guo et al. 2018. Immunity. 49(3):531-544 . PubMed
- Klein O, et al. 2019. J Allergy Clin Immunol. 144:1074. PubMed
- Zhang M, et al. 2017. Mol Med Rep. 15:4291. PubMed
- Hirota K et al. 2018. Immunity. 48(6):1220-1232 . PubMed
- Kastenschmidt JM, et al. 2021. Cell Rep. 35:108997. PubMed
- Dutton EE, et al. 2018. Wellcome Open Res. 2:117. PubMed
- RRID
- AB_2561914 (BioLegend Cat. No. 145303) AB_2561915 (BioLegend Cat. No. 145304)
- Structure
- 63 kD, IL-1 receptor family member, single pass type I membrane protein
- Distribution
-
Mast cells, Th2 cells, and fibroblasts
- Function
- Following interaction with IL-33, it recruits MyD88, Irak1, Irak4 and Traf6 followed by phosphorylation of the MAP/ERK pathway.
- Interaction
- Interacts with MyD88, Irak1, Irak4 and Traf6
- Ligand/Receptor
- IL-33
- Cell Type
- Fibroblasts, Mast cells, Th2
- Biology Area
- Immunology, Innate Immunity
- Molecular Family
- Cytokine/Chemokine Receptors
- Antigen References
-
1. Yanagisawa K, et al. 1993. FEBS Lett. 318:83.
2. Schmitt E, et al. 1990. Cytokine 6:407.
3. Yanagisawa K, et al. 1992. FEBS Lett. 302:51.
4. Takagi T, et al. 1993. Biochim Biophys Acta. 1178:194.
- Gene ID
- 17082 View all products for this Gene ID
- UniProt
- View information about IL-33Ralpha on UniProt.org
