Brilliant Violet 421™ anti-mouse IL-33R&alph
- 产品名称：
- Brilliant Violet 421™ anti-mouse IL-33R&alph
- 产品类别：
- 抗体
- 产品编号：
- 145309
- 产品应用：
- 145309
- Verified Reactivity
- Mouse
- Antibody Type
- Monoclonal
- Host Species
- Rat
- Immunogen
- IL-33Rα-hFcγ1 fusion protein.
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA).
- Preparation
- The antibody was purified by affinity chromatography and conjugated with Brilliant Violet 421? under optimal conditions.
- Concentration
- 0.2 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.5 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.
Brilliant Violet 421? excites at 405 nm and emits at 421 nm. The standard bandpass filter 450/50 nm is recommended for detection. Brilliant Violet 421? is a trademark of Sirigen Group Ltd.
Learn more about Brilliant Violet?.
This product is subject to proprietary rights of Sirigen Inc. and is made and sold under license from Sirigen Inc. The purchase of this product conveys to the buyer a non-transferable right to use the purchased product for research purposes only. This product may not be resold or incorporated in any manner into another product for resale. Any use for therapeutics or diagnostics is strictly prohibited. This product is covered by U.S. Patent(s), pending patent applications and foreign equivalents. - Excitation Laser
- Violet Laser (405 nm)
- Application References
(PubMed link indicates BioLegend citation) -
- Hashiguchi M, et al. 2014. Eur. J. Immunology. (FC) PubMed
- Product Citations
-
- Petrova T, et al. 2020. Sci Rep. 10:3479. PubMed
- Delacher M, et al. 2021. Immunity. 54(4):702-720.e17. PubMed
- McCarthy PC, et al. 2019. Immunol Cell Biol. 97:54. PubMed
- Morimoto Y, et al. 2018. Immunity. 49:134. PubMed
- Nagashima H et al. 2019. Immunity. 51(4):682-695 . PubMed
- Baja?a S, et al. 2022. iScience. 25:103732. PubMed
- Fujimoto M, et al. 2022. Nat Commun. 13:5408. PubMed
- Chetty A, et al. 2021. Cell Host Microbe. 29:579. PubMed
- Chen Z, et al. 2020. Immunity. 54(1):151-163.e6. PubMed
- RRID
- AB_2565634 (BioLegend Cat. No. 145309)
- Structure
- 63 kD, IL-1 receptor family member, single pass type I membrane protein
- Distribution
-
Mast cells, Th2 cells, and fibroblasts
- Function
- Following interaction with IL-33, it recruits MyD88, Irak1, Irak4 and Traf6 followed by phosphorylation of the MAP/ERK pathway.
- Interaction
- Interacts with MyD88, Irak1, Irak4 and Traf6
- Ligand/Receptor
- IL-33
- Cell Type
- Fibroblasts, Mast cells, Th2
- Biology Area
- Immunology, Innate Immunity
- Molecular Family
- Cytokine/Chemokine Receptors
- Antigen References
-
1. Yanagisawa K, et al. 1993. FEBS Lett. 318:83.
2. Schmitt E, et al. 1990. Cytokine 6:407.
3. Yanagisawa K, et al. 1992. FEBS Lett. 302:51.
4. Takagi T, et al. 1993. Biochim Biophys Acta. 1178:194.
- Gene ID
- 17082 View all products for this Gene ID
- UniProt
- View information about IL-33Ralpha on UniProt.org
