APC anti-mouse IL-33Rα (IL1RL1, ST2) Antibod
- 产品名称：
- APC anti-mouse IL-33Rα (IL1RL1, ST2) Antibod
- 产品类别：
- 抗体
- 产品编号：
- 145305
- 产品应用：
- 145305
- Verified Reactivity
- Mouse
- Antibody Type
- Monoclonal
- Host Species
- Rat
- Immunogen
- IL-33Rα-hFcγ1 fusion protein.
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions.
- Concentration
- 0.2 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤1.0 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Excitation Laser
- Red Laser (633 nm)
- Application References
(PubMed link indicates BioLegend citation) -
- Hashiguchi M, et al. 2014. Eur. J. Immunology. (FC) PubMed
- Product Citations
-
- Saxena A, et al. 2013. J Immunol. 191:4838. PubMed
- Delacher M, et al. 2021. Immunity. 54(4):702-720.e17. PubMed
- Hayatsu N et al. 2017. Immunity. 47(2):268-283 . PubMed
- He J, et al. 2020. Cell Reports. 29(9):2718-2730.e6.. PubMed
- Loh Z, et al. 2020. PLOS Pathogens. 16(7):e1008651. PubMed
- Colliou N, et al. 2015. Toxins. 7: 3805 - 3817. PubMed
- Kanemaru K, et al. 2015. PLoS One. 10: 0144436. PubMed
- Li Z et al. 2018. Immunity. 49(4):640-653 . PubMed
- RRID
- AB_2561916 (BioLegend Cat. No. 145305) AB_2561917 (BioLegend Cat. No. 145306)
- Structure
- 63 kD, IL-1 receptor family member, single pass type I membrane protein
- Distribution
-
Mast cells, Th2 cells, and fibroblasts
- Function
- Following interaction with IL-33, it recruits MyD88, Irak1, Irak4 and Traf6 followed by phosphorylation of the MAP/ERK pathway.
- Interaction
- Interacts with MyD88, Irak1, Irak4 and Traf6
- Ligand/Receptor
- IL-33
- Cell Type
- Fibroblasts, Mast cells, Th2
- Biology Area
- Immunology, Innate Immunity
- Molecular Family
- Cytokine/Chemokine Receptors
- Antigen References
-
1. Yanagisawa K, et al. 1993. FEBS Lett. 318:83.
2. Schmitt E, et al. 1990. Cytokine 6:407.
3. Yanagisawa K, et al. 1992. FEBS Lett. 302:51.
4. Takagi T, et al. 1993. Biochim Biophys Acta. 1178:194.
- Gene ID
- 17082 View all products for this Gene ID
- UniProt
- View information about IL-33Ralpha on UniProt.org
