PE/Cyanine7 anti-mouse IL-33Rα (ST2) Antibod
- 产品名称：
- PE/Cyanine7 anti-mouse IL-33Rα (ST2) Antibod
- 产品类别：
- 抗体
- 产品编号：
- 146609
- 产品应用：
- 146609
- Verified Reactivity
- Mouse
- Antibody Type
- Monoclonal
- Host Species
- Rat
- Immunogen
- IL-33Rα-hFcγ 1 fusion protein
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography and conjugated with PE/Cyanine7 under optimal conditions.
- Concentration
- 0.2 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is = 0.125 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Excitation Laser
- Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
- Additional Product Notes
- BioLegend is in the process of converting the name PE/Cy7 to PE/Cyanine7. The dye molecule remains the same, so you should expect the same quality and performance from our PE/Cyanine7 products. Please contact Technical Service if you have any questions.
- Application References
(PubMed link indicates BioLegend citation) -
- Hashiguchi M, et al. 2014. Eur. J. Immunology. (FC, Block) PubMed
- RRID
- AB_2728178 (BioLegend Cat. No. 146609) AB_2728179 (BioLegend Cat. No. 146610)
- Structure
- Approximately 63kD, IL-1 receptor family member, single pass type I membrane protein
- Distribution
-
Mast cells, Th2 cells and fibroblasts
- Function
- Interacts with IL-33 and recruits MyD88, Irak1, Irak4 and Traf6 followed by phosphorylation of the MAP/ERK pathway
- Interaction
- Interacts with MyD88, Irak1, Irak4 and Traf6
- Ligand/Receptor
- IL-33
- Cell Type
- Mast cells, Th2, Fibroblasts
- Biology Area
- Immunology, Innate Immunity
- Molecular Family
- Cytokine/Chemokine Receptors
- Antigen References
-
- Yanagisawa K, et al. 1993. FEBS Lett. 318:83.
- Schmitt E,?et al. 1990. Cytokine. 6:407.
- Yanagisawa K, et al. 1992. FEBS Lett. 302:51.
- Takagi T,?et al. 1993. Biochim. Biophys. Acta. 1178:194.
- Gene ID
- 17082 View all products for this Gene ID
- UniProt
- View information about IL-33Ralpha on UniProt.org
