PE anti-mouse IL-33Rα (ST2) Antibody
- 产品名称：
- PE anti-mouse IL-33Rα (ST2) Antibody
- 产品类别：
- 抗体
- 产品编号：
- 146608
- 产品应用：
- 146608
- Verified Reactivity
- Mouse
- Antibody Type
- Monoclonal
- Host Species
- Rat
- Immunogen
- IL-33Rα-hFcγ 1 fusion protein
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.
- Concentration
- 0.2 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Excitation Laser
- Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
- Application References
(PubMed link indicates BioLegend citation) -
- Hashiguchi M, et al. 2014. Eur. J. Immunology. (FC, Block) PubMed
- Product Citations
-
- Wiesner DL, et al. 2020. Cell Host Microbe. 614:27. PubMed
- Delacher M, et al. 2021. Immunity. 54(4):702-720.e17. PubMed
- Baja?a S, et al. 2022. iScience. 25:103732. PubMed
- Chang MH, et al. 2021. Cell Rep. 37:109902. PubMed
- RRID
- AB_2728176 (BioLegend Cat. No. 146607) AB_2728177 (BioLegend Cat. No. 146608)
- Structure
- Approximately 63kD, IL-1 receptor family member, single pass type I membrane protein
- Distribution
-
Mast cells, Th2 cells and fibroblasts
- Function
- Interacts with IL-33 and recruits MyD88, Irak1, Irak4 and Traf6 followed by phosphorylation of the MAP/ERK pathway
- Interaction
- Interacts with MyD88, Irak1, Irak4 and Traf6
- Ligand/Receptor
- IL-33
- Cell Type
- Mast cells, Th2, Fibroblasts
- Biology Area
- Immunology, Innate Immunity
- Molecular Family
- Cytokine/Chemokine Receptors
- Antigen References
-
- Yanagisawa K, et al. 1993. FEBS Lett. 318:83.
- Schmitt E,?et al. 1990. Cytokine. 6:407.
- Yanagisawa K, et al. 1992. FEBS Lett. 302:51.
- Takagi T,?et al. 1993. Biochim. Biophys. Acta. 1178:194.
- Gene ID
- 17082 View all products for this Gene ID
- UniProt
- View information about IL-33Ralpha on UniProt.org
