Purified anti-Cyclin D3 Antibody -上海雅吉生物科技有限公司

规格	价格	库存
100µg	￥ 3710	1

规格

价格

库存

100µg

￥ 3710

Product Details

Verified Reactivity: Human, Mouse, Rat
Antibody Type: Monoclonal
Host Species: Mouse
Immunogen: Full length Cyclin D3 of human origin.
Formulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation: The antibody was purified by affinity chromatography.
Concentration: 0.5 mg/ml
Storage & Handling: The antibody solution should be stored undiluted between 2°C and 8°C.
Application: WB -?Quality tested
ICFC, KO/KD-WB -?Verified
Recommended Usage: Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 0.5 - 2.5 ?g per ml. For intracellular flow cytometric staining, the suggested use of this reagent is ≤0.25 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.
RRID: AB_2572190 (BioLegend Cat. No. 684902)

Structure: Major isoform has 291 amino acids and predicted molecular weight of 33 kD.
Distribution: Nucleus, cytoplasm and cell membrane.
Function: Regulatory component of the cyclin D3-CDK4 (DC) complex that phosphorylates and inhibits members of the retinoblastoma (RB) protein family including RB1 and regulates the cell-cycle during G₁/S transition.
Interaction: CDK14, CDK4, CDK6, ATF5, EIF3K, CDKN1A, ICP0, POLR3GL, and TFIP11.
Biology Area: Cell Biology, Cell Cycle/DNA Replication, Signal Transduction
Antigen References: 1. Liu W, et al. 2004. Biochem. Biophys. Res. Commun. 321:954.
2. Sherr CJ. 1993. Cell 73:1059.
3. Saavedra-?vila NA. 2014. Proc. Natl. Acad. Sci. USA 111:E3405.
4. Lukas J, et al. 1996. Mol. Cell Biol. 16:6917.
5. Wang W, et al. 2012. Carcinogenesis. 33:1113.
6. Cato MH, et al. 2011. Mol. Cell Biol. 31:127.
7. Zhang Q, et al. 2014. Mol. Cell Endocrinol. 382:583.
8. Chi Y, et al. 2015. Cancer Cell Int. 15:89.
Gene ID: 896 View all products for this Gene ID
UniProt: View information about Cyclin D3 on UniProt.org