Purified anti-human CD276 (B7-H3) Antibody
- 产品名称:
- Purified anti-human CD276 (B7-H3) Antibody
- 产品类别:
- 抗体
- 产品编号:
- 331602
- 产品应用:
- 331602
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.5 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.
- RRID
- AB_1279202 (BioLegend Cat. No. 331602)
- Structure
- About 49.7 KD transmembrane protein characterized by extracellular IgV and IgC domains.
- Distribution
-
B7-H3 is expressed on professional APCs, including B cells, dendritic cells, and macrophages. It is reported to express on a minor fraction of CD4+ and CD8+ cells.
- Ligand/Receptor
- The receptor has not been identified, but it seems to be expressed on activated T cells.
- Bioactivity
- B7-H3 is a negative regulator of T cell activation and IL-2 production.
- Cell Type
- Antigen-presenting cells, B cells
- Biology Area
- Costimulatory Molecules, Immunology
- Molecular Family
- CD Molecules
- Antigen References
-
1. Sun M, et al. 2002. J. Immunology. 168:6294
2. Xu J, et al. 2006. Cellular and Molecular Immunology. 3:235
- Gene ID
- 80381 View all products for this Gene ID
- UniProt
- View information about CD276 on UniProt.org