PE anti-human CD276 (B7-H3) Antibody
- 产品名称：
- PE anti-human CD276 (B7-H3) Antibody
- 产品类别：
- 抗体
- 产品编号：
- 331605
- 产品应用：
- 331605
[价格]
| 规格 |
价格 |
库存 |
| 25tests |
￥ 1876 |
1 |
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.
- Excitation Laser
- Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
- Product Citations
-
- Shao L, et al. 2021. Cell Death Discov. 7:145. PubMed
- Brignole C, et al. 2021. J Exp Clin Cancer Res. 40:180. PubMed
- Zeng W, et al. 2017. Front Immunol. 0.806944444. PubMed
- Huang C, et al. 2020. Theranostics. 10:10498. PubMed
- Liu T, et al. 2022. Front Immunol. 13:901349. PubMed
- Xie J, et al. 2021. FEBS Open Bio. 11:2977. PubMed
- Lavoie RR, et al. 2021. Cancers (Basel). 13:. PubMed
- Li H, et al. 2020. Front Oncol. 1.477083333. PubMed
- RRID
- AB_1279200 (BioLegend Cat. No. 331605) AB_1279197 (BioLegend Cat. No. 331606)
- Structure
- About 49.7 KD transmembrane protein characterized by extracellular IgV and IgC domains.
- Distribution
-
B7-H3 is expressed on professional APCs, including B cells, dendritic cells, and macrophages. It is reported to express on a minor fraction of CD4+ and CD8+ cells.
- Ligand/Receptor
- The receptor has not been identified, but it seems to be expressed on activated T cells.
- Bioactivity
- B7-H3 is a negative regulator of T cell activation and IL-2 production.
- Cell Type
- Antigen-presenting cells, B cells
- Biology Area
- Costimulatory Molecules, Immunology
- Molecular Family
- CD Molecules
- Antigen References
-
1. Sun M, et al. 2002. J. Immunology. 168:6294
2. Xu J, et al. 2006. Cellular and Molecular Immunology. 3:235
- Gene ID
- 80381 View all products for this Gene ID
- UniProt
- View information about CD276 on UniProt.org
