PE/Cyanine7 anti-human CD227 (MUC-1) Antibody
- 产品名称：
- PE/Cyanine7 anti-human CD227 (MUC-1) Antibody
- 产品类别：
- 抗体
- 产品编号：
- 355605
- 产品应用：
- 355605
[价格]
| 规格 |
价格 |
库存 |
| 25tests |
￥ 2464 |
1 |
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Jurkat cells transfected with MUC1
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography and conjugated with PE/Cyanine7 under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.
- Excitation Laser
- Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
- Application Notes
This clone shows stronger binding to the glycosylated compared to the non-glycosylated peptide1.
- Additional Product Notes
- BioLegend is in the process of converting the name PE/Cy7 to PE/Cyanine7. The dye molecule remains the same, so you should expect the same quality and performance from our PE/Cyanine7 products. Please contact Technical Service if you have any questions.
- Application References
(PubMed link indicates BioLegend citation) -
- Song W, et al. 2012. Int. J Oncol. 41:1977. PubMed
- Product Citations
-
- Rodrigues Toste de Carvalho AL, et al. 2021. Nat Protoc. 16:1802. PubMed
- RRID
- AB_2564194 (BioLegend Cat. No. 355605) AB_2564195 (BioLegend Cat. No. 355606)
- Structure
- 500-1000 kD proteoglycan (glycosylated form)
- Distribution
-
Activated T cells, mucosal epithelial cells, aberrantly expressed in most breast cancers
- Interaction
- Complexes with SOS1 and Grb2 in RAS signaling
- Ligand/Receptor
- ICAM-1 and Her2/neu (ErbB2)
- Cell Type
- Dendritic cells, Epithelial cells, T cells
- Biology Area
- Immunology, Innate Immunity
- Molecular Family
- CD Molecules
- Antigen References
-
1. Gendler SJ. 2001. J. Mammary Gland Biol. Neoplasia. 6:339.
2. Agrawal B, et al. 1998. Cancer Res. 58:4079.
3. Rahn JJ, et al. 2004. J. Biol. Chem. 279:29386.
- Gene ID
- 4582 View all products for this Gene ID
- UniProt
- View information about CD227 on UniProt.org
