APC anti-human CD227 (MUC-1) Antibody
- 产品名称：
- APC anti-human CD227 (MUC-1) Antibody
- 产品类别：
- 抗体
- 产品编号：
- 355607
- 产品应用：
- 355607
[价格]
| 规格 |
价格 |
库存 |
| 25tests |
￥ 1834 |
1 |
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Jurkat cells transfected with MUC1
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.
- Excitation Laser
- Red Laser (633 nm)
- Application Notes
This clone shows stronger binding to the glycosylated compared to the non-glycosylated peptide1.
- Application References
(PubMed link indicates BioLegend citation) -
- Song W, et al. 2012. Int. J Oncol. 41:1977. PubMed
- Product Citations
-
- Bhattacharya S, et al. 2020. Front Bioeng Biotechnol. 1.055555556. PubMed
- Wang J, et al. 2022. Front Immunol. 13:863346. PubMed
- Norgard RJ, et al. 2021. EMBO Rep. 22:e51872. PubMed
- Rodrigues Toste de Carvalho AL, et al. 2021. Nat Protoc. 16:1802. PubMed
- RRID
- AB_2565311 (BioLegend Cat. No. 355607) AB_2565312 (BioLegend Cat. No. 355608)
- Structure
- 500-1000 kD proteoglycan (glycosylated form)
- Distribution
-
Activated T cells, mucosal epithelial cells, aberrantly expressed in most breast cancers
- Interaction
- Complexes with SOS1 and Grb2 in RAS signaling
- Ligand/Receptor
- ICAM-1 and Her2/neu (ErbB2)
- Cell Type
- Dendritic cells, Epithelial cells, T cells
- Biology Area
- Immunology, Innate Immunity
- Molecular Family
- CD Molecules
- Antigen References
-
1. Gendler SJ. 2001. J. Mammary Gland Biol. Neoplasia. 6:339.
2. Agrawal B, et al. 1998. Cancer Res. 58:4079.
3. Rahn JJ, et al. 2004. J. Biol. Chem. 279:29386.
- Gene ID
- 4582 View all products for this Gene ID
- UniProt
- View information about CD227 on UniProt.org
